Amar A D, Singer B, Chabra K
Clin Pediatr (Phila). 1976 Jun;15(6):562-9. doi: 10.1177/000992287601500612.
Early recognition, adequate treatment, close observation, and systematic follow-up over a long period are essential to renal salvage in the child with vesicoureteral reflux. The decision whether and when to operate is made on a balance of factors by the pediatrician-urologist team. Among 236 patients with reflux diagnosed during childhood, reflux was stopped in 55 per cent of those treated medically and in 98 per cent of the more severe cases who were treated by ureteral reimplantation. Chronic pyelonephritis appeared or worsened during medical management in 12 per cent; no child showed new pyelonephritic scars or worsening of pyelonephritis after ureteral reimplantation.
对于患有膀胱输尿管反流的儿童,早期识别、充分治疗、密切观察以及长期系统随访对于挽救肾脏至关重要。小儿科医生 - 泌尿科医生团队会综合考虑多种因素来决定是否以及何时进行手术。在236例儿童期诊断出反流的患者中,接受药物治疗的患者中有55%的反流停止,而在接受输尿管再植术治疗的更严重病例中,这一比例为98%。在药物治疗期间,12%的患者出现或加重了慢性肾盂肾炎;输尿管再植术后,没有儿童出现新的肾盂肾炎瘢痕或肾盂肾炎恶化。