Stoker Jaap, Rociu Elena, Bosch J L H Ruud, Messelink Embert J, van der Hulst Victor P M, Groenendijk Annette G, Eijkemans Marinus J C, Laméris Johan S
Department of Radiology, Academic Medical Center, University of Amsterdam, P.O. Box 22700, 1100 DE Amsterdam, The Netherlands.
Eur Radiol. 2003 Aug;13(8):2031-7. doi: 10.1007/s00330-003-1855-2. Epub 2003 Apr 12.
The causes of stress urinary incontinence are not completely known. Recent papers have stressed the importance of more anatomical information, which may help to elucidate the mechanism of stress urinary incontinence. The purpose of this study was to evaluate the prevalence of lesions of the urethral support mechanism and lesions (defects and scars, thinning) of levator ani muscle with endovaginal MRI in a case-control study. Forty women (median age 52 years, age range 40-65 years)--20 patients with stress urinary incontinence (cases) and 20 age-matched healthy volunteers (controls)--underwent endovaginal MRI: axial, coronal, and sagittal T2-weighted turbo spin echo. The examinations were evaluated for the presence of lesions of urethral supporting structures and levator ani and scar tissue of the levator ani. The thickness of the levator ani muscle was measured. Lesions of the urethral support system and levator ani were significantly more prevalent in cases than in controls ( p<0.01). Median levator ani thickness in patients was significantly lower than in healthy controls [2.5 mm (range 0.9-4.1 mm) vs 3.9 mm (range 1.4-7 mm)] ( p<0.01). This study indicates a relationship between stress urine incontinence and the presence of lesions of the urethral support and levator ani and levator ani thinning.
压力性尿失禁的病因尚不完全清楚。近期的论文强调了获取更多解剖学信息的重要性,这可能有助于阐明压力性尿失禁的机制。本研究的目的是在一项病例对照研究中,通过阴道内磁共振成像(MRI)评估尿道支撑机制病变以及肛提肌病变(缺陷、瘢痕、变薄)的发生率。40名女性(年龄中位数52岁,年龄范围40 - 65岁)——20例压力性尿失禁患者(病例组)和20名年龄匹配的健康志愿者(对照组)——接受了阴道内MRI检查:轴位、冠状位和矢状位T2加权快速自旋回波成像。对检查结果评估尿道支撑结构、肛提肌和肛提肌瘢痕组织的病变情况,并测量肛提肌厚度。病例组尿道支撑系统和肛提肌的病变发生率显著高于对照组(p<0.01)。患者的肛提肌厚度中位数显著低于健康对照组[2.5毫米(范围0.9 - 4.1毫米)对3.9毫米(范围1.4 - 7毫米)](p<0.01)。本研究表明压力性尿失禁与尿道支撑结构和肛提肌病变以及肛提肌变薄之间存在关联。