Sasaki Masahiro, Sano Masaaki, Sato Kazuhiro, Fukui Sin, Izumiyama Noriko, Ito Takefumi, Kashima Masayuki, Kagaya Manabu, Miura Mamoru
Second Department of Internal Medicine, Akita University School of Medicine.
Nihon Kokyuki Gakkai Zasshi. 2002 Dec;40(12):960-4.
Few cases of Mycoplasma pneumoniae and Chlamydia pneumoniae coinfection in pneumonia have been reported in adults. We report a case of such a double infection in a young adult. A 16-year-old boy was admitted to our hospital with dry cough and fever. Laboratory findings revealed elevated serum GOT and GPT levels. The patient had been administered a beta-lactam antibiotic before admission to our hospital. Antibodies to M. pneumoniae were significantly elevated. Titers of IgM and IgG specific for C. pneumoniae titer were high, as measured by the enzyme-linked immunosorbent assay method. The patient was treated with clarithromycin and discharged after a satisfactory recovery. M. pneumoniae and C. pneumoniae may act as cofactors in community-acquired pneumonia. Further studies are needed to clarify the relationships of these pathogens to community-acquired pneumonia.
成人肺炎中肺炎支原体和肺炎衣原体合并感染的病例报道较少。我们报告一例年轻成人的此类双重感染病例。一名16岁男孩因干咳和发热入院。实验室检查结果显示血清谷草转氨酶和谷丙转氨酶水平升高。该患者在入院前曾接受β-内酰胺类抗生素治疗。肺炎支原体抗体显著升高。通过酶联免疫吸附测定法测得，肺炎衣原体特异性IgM和IgG滴度较高。该患者接受克拉霉素治疗，康复良好后出院。肺炎支原体和肺炎衣原体可能是社区获得性肺炎的辅助因子。需要进一步研究以阐明这些病原体与社区获得性肺炎的关系。
