Oldridge N, Perkins A, Hodes Z
Indiana University Center for Aging Research School of Allied Health Sciences, Regenstrief Institute for Health Care, RG6, 1050 Wishard Boulevard, Indianapolis, IN 46202, USA.
Monaldi Arch Chest Dis. 2002 May;58(1):10-8.
We were interested in the feasibility of existing valid specific health-related quality of life [HRQL] instruments, designed for patients with heart failure, angina pectoris, or myocardial infarction [MI], being used to make outcome comparisons among pure or mixed populations of patients with these heart disease diagnoses.
A battery of specific HRQL questionnaires, including the Minnesota Living with Heart Failure questionnaire, the Seattle Angina Questionnaire, the MacNew Heart Disease questionnaire, the generic SF-36 health status survey, and the Hospital Anxiety and Depression Scale, was mailed to the 205 patients with current mailing addresses and returned by 161 patients [78.5%].
None of the 22 specific and generic HRQL scales differed by diagnostic category. There were significant correlations between all corresponding HRQL scales in the MLHF, SAQ, and MacNew instruments as well as between each of the corresponding specific and generic SF-36 scales. In all cases, the correlations between the specific HRQL scales were numerically greater than those between the specific instruments and the generic SF-36 scales. Patients with and without either anxiety or depression differed significantly on each of the specific HRQL instruments and on the majority of the SF-36 scales.
The results of this investigation suggest that a common HRQL instrument for patients with heart failure, angina, and MI may prove to be useful when there is an interest in comparing outcomes among pure or mixed populations of patients with heart disease.
我们关注的是，为心力衰竭、心绞痛或心肌梗死（MI）患者设计的现有有效的特定健康相关生活质量（HRQL）工具，用于对患有这些心脏病诊断的单纯或混合患者群体进行结果比较的可行性。
一组特定的HRQL问卷，包括明尼苏达心力衰竭生活问卷、西雅图心绞痛问卷、麦克纽心脏病问卷、通用的SF-36健康状况调查以及医院焦虑抑郁量表，被邮寄给有当前邮寄地址的205名患者，161名患者（78.5%）回复了问卷。
22个特定和通用的HRQL量表在诊断类别上均无差异。MLHF、SAQ和麦克纽工具中所有相应的HRQL量表之间以及每个相应的特定和通用SF-36量表之间均存在显著相关性。在所有情况下，特定HRQL量表之间的相关性在数值上大于特定工具与通用SF-36量表之间的相关性。有焦虑或抑郁与无焦虑或抑郁的患者在每个特定HRQL工具和大多数SF-36量表上均存在显著差异。
本研究结果表明，当有兴趣比较患有心脏病的单纯或混合患者群体的结果时，一种用于心力衰竭、心绞痛和心肌梗死患者的通用HRQL工具可能会被证明是有用的。
