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咪喹莫特治疗顽固性疣:一种新的治疗选择?

[Imiquimod in the treatment of recalcitrant warts: a new therapy option?].

作者信息

Hesterberg U, Böhlen L M, Brand C U

机构信息

Dermatologische Universitätsklinik, Inselspital Bern.

出版信息

Praxis (Bern 1994). 2003 Mar 19;92(12):535-9. doi: 10.1024/0369-8394.92.12.535.

DOI:10.1024/0369-8394.92.12.535
PMID:12693144
Abstract

Recalcitrants viral warts can pose a therapeutic challenge to the treating physician. In a clinical study, we documented the effect of imiquimod 5% cream (Aldara) on recalcitrants warts in 22 patients. A complete and partial clearing of the warts was achieved in 41% and 50%, respectively. In only 9% of patients no improvement could be observed. Beside the very often observed perilesional erythema, which correlated well with good treatment response, no relevant side effects were documented. Imiquimod 5% cream (Aldara) is an efficient, easy to perform ambulatory treatment modality for recalcitrants HPV induced warts with few side effects.

摘要

顽固性病毒疣会给治疗医生带来治疗挑战。在一项临床研究中,我们记录了5%咪喹莫特乳膏(艾达乐)对22例顽固性疣的疗效。疣体完全清除和部分清除的比例分别为41%和50%。仅9%的患者未观察到改善。除了经常观察到的与良好治疗反应密切相关的皮损周围红斑外,未记录到相关副作用。5%咪喹莫特乳膏(艾达乐)是一种治疗顽固性人乳头瘤病毒引起的疣的有效、易于实施的门诊治疗方式,副作用少。

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引用本文的文献

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Immunomodulators in warts: Unexplored or ineffective?疣中的免疫调节剂:未被探索还是无效?
Indian J Dermatol. 2015 Mar-Apr;60(2):118-29. doi: 10.4103/0019-5154.152502.
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An armamentarium of wart treatments.一套疣治疗方法。
Clin Med Res. 2006 Dec;4(4):273-93. doi: 10.3121/cmr.4.4.273.