Chiriac Carmen-Florina, Gavriliţă Lorica
Catedra de Anatomie Patologică, U.M.F. Iaşi.
Pneumologia. 2002 Oct-Dec;51(4):277-80.
Lung cancer mortality is a major public health problem. Smoking, the most important aetiological factor, is responsible in almost 85% of lung cancer cases. Tobacco smoking is associated with almost all histological types of lung cancer. In a retrospective study, carried out on 304 patients (244 men and 60 females; average age 63.4 years), diagnosed between January 1st, 2000, and December 31st, 2001, we investigated the importance of smoking, the age of beginning of smoking and the association of different histological types of lung cancer with smoking. Twenty-one patients were non-smokers, 123 ex-smokers and 160 current smokers, with an average number of PY of 43 (2-120). Age at the start of smoking was between 10-19 years for the most important number of patients. In concordance with others studies, squamous cell carcinoma was on the first place in men (47.1%) and in smokers (43.81%), while in the women and non-smokers it was an adenocarcinoma (33.3%) and (52.38%). The squamous cell carcinoma remains the most frequently found in our study; the increase in adenocarcinoma is associated with changes in the composition and consumption of cigarettes.
肺癌死亡率是一个重大的公共卫生问题。吸烟是最重要的病因，几乎85%的肺癌病例都与之相关。吸烟与几乎所有组织学类型的肺癌都有关联。在一项对2000年1月1日至2001年12月31日期间诊断的304例患者（244名男性和60名女性；平均年龄63.4岁）进行的回顾性研究中，我们调查了吸烟的重要性、开始吸烟的年龄以及不同组织学类型的肺癌与吸烟的关联。21例患者不吸烟，123例为既往吸烟者，160例为当前吸烟者，平均累积吸烟年数为43（2 - 120）。开始吸烟的年龄在大多数患者中为10 - 19岁。与其他研究一致，鳞状细胞癌在男性（47.1%）和吸烟者（43.81%）中位居首位，而在女性和不吸烟者中则是腺癌（33.3%）和（52.38%）。鳞状细胞癌在我们的研究中仍然是最常见的；腺癌的增加与香烟成分和消费量的变化有关。
