Weiner Robin, Collison Patrick J
S D J Med. 2003 Mar;56(3):103-7.
A cohort of 191 children with recurrent otitis media and persistent middle ear effusion underwent myringotomy and tubes, at which time middle ear cultures were taken. The indications, fluid type, culture and sensitivity results, and pre- and post-procedure frequency of otitis media were evaluated. Sixty-seven percent of the effusions were mucoid in nature, and 24% of cultures grew pathogens, including Hemophilus influenzae, Streptococcus pneumoniae, Moraxella catarrhalis, and Staphylococcus aureus in that order of frequency. A relatively high rate of antibiotic resistance was noted, with 75% of Streptococcus pneumoniae being penicillin resistant. Prognosis with respect to recurrent otitis media was favorable after myringotomy and tubes, even in children with antibiotic-resistant organisms.
191名患有复发性中耳炎和持续性中耳积液的儿童接受了鼓膜切开置管手术，同时采集了中耳培养物。对手术指征、积液类型、培养及药敏结果以及术前和术后中耳炎的发作频率进行了评估。67%的积液本质上是黏液性的，24%的培养物培养出病原体，依次为流感嗜血杆菌、肺炎链球菌、卡他莫拉菌和金黄色葡萄球菌。观察到抗生素耐药率相对较高，75%的肺炎链球菌对青霉素耐药。即使是对抗生素耐药菌感染的儿童，鼓膜切开置管术后复发性中耳炎的预后也较好。
