Dhanaraj M, Jayavelu A
Department of Neurology, Government Stanley Medical College and Hospital, Chennai-600 001.
J Assoc Physicians India. 2003 Jan;51:43-4.
To assess the efficacy of intermittent administration of clobazam to prevent hot water epilepsy.
Ten adults with 1:1 ratio of hot water epilepsy were administered 10 mg of clobazam about one and half hour before each hot water head bath. They were followed up for nine months.
Nine out of 10 patients did not develop recurrence of seizure following regular hot water head bath during nine month follow up period. One continued to get mild giddiness. The adverse effects observed were sleepiness in two and fall in memory in one on the day of drug intake.
Intermittent oral administration of clobazam before hot water bath alone is effective in preventing hot water epilepsy with 1:1 ratio.
评估间歇性服用氯巴占预防热水性癫痫的疗效。
选取10名患热水性癫痫的成年人，男女比例为1:1，在每次热水洗头前约一个半小时给予10毫克氯巴占。对他们进行了9个月的随访。
在9个月的随访期内，10名患者中有9名在定期热水洗头后未出现癫痫复发。1名患者仍有轻度头晕。观察到的不良反应为服药当天2人出现嗜睡，1人记忆力下降。
仅在热水浴前间歇性口服氯巴占对预防1:1比例的热水性癫痫有效。
