Binder Monica I, Chua Jimmy, Kaiser Peter K, Mehta Neil, Isada Carlos M
Department of Infectious Disease, Cleveland Clinic Foundation, Cleveland, Ohio 44195, USA.
Scand J Infect Dis. 2003;35(2):133-6. doi: 10.1080/00365540410000921.
Endogenous endophthalmitis due to Actinobacillus actinomycetemcomitans is an unusual disease with serious sequelae. Of the 4 cases published in the literature only 1 recovered useful vision after treatment. This study reports on 1 additional patient and expands on the previously described brief ophthalmology case report of another patient with marked visual impairment at presentation and good visual recovery after treatment. Of the 5 patients described, 4 had pre-existing heart abnormalities, 3 had permanent pacemakers and 2 had periodontal disease. Definite endocarditis by Duke criteria was present in 3 patients. Endocarditis should be ruled out in every patient with A. actinomycetemcomitans endophthalmitis, even in the absence of systemic complaints and prior penicillin prophylaxis. Eye specimen cultures should be incubated for 10 d. A thorough dental examination should be done in each patient and any periodontal disease should be promptly treated.
由伴放线放线杆菌引起的内源性眼内炎是一种罕见疾病,会导致严重后遗症。文献报道的4例病例中,仅有1例在治疗后恢复了有用视力。本研究报告了另外1例患者,并对之前描述的另1例患者的简短眼科病例报告进行了扩展,该患者就诊时视力严重受损,治疗后视力恢复良好。在描述的5例患者中,4例有既往心脏异常,3例有永久性起搏器,2例有牙周病。根据杜克标准,3例患者存在明确的心内膜炎。对于每例伴放线放线杆菌性眼内炎患者,即使没有全身症状和既往青霉素预防治疗史,也应排除心内膜炎。眼标本培养应孵育10天。应对每位患者进行全面的牙科检查,任何牙周病都应及时治疗。