Retamar Roberto Adrián, Kien M C, Chouela E N
Department of Dermatology, Hospital General de Agudos Dr Cosme Argerich, Buenos Aires, Argentina.
Int J Dermatol. 2003 Apr;42(4):305-7. doi: 10.1046/j.1365-4362.2003.01304.x.
Zoon's balanitis is a chronic erosive process of the penis. The lesions are refractory to conservative topical and some surgical therapy, and frequently require circumcision as a curative measure.
Fifteen patients with a clinical and histopathologic diagnosis of Zoon's balanitis were studied between October 1991 and October 2001. Five were treated with a carbon dioxide laser.
The ages of the patients ranged from 36 to 69 years (average, 50.8 years). All the men were uncircumcised and presented with a discharge and erythematous lesions on the glans penis; the balanopreputial fold was affected in 10 patients and eight had a lesion on the internal surface of the prepuce. One patient was human immunodeficiency virus positive. Five were treated with a carbon dioxide laser. Two relapsed 1 and 3 years later, respectively, and the remaining three have been followed up for 2, 5, and 6 years, respectively, without relapse. One patient developed lichen sclerosus et atrophicus of the prepuce.
We have presented our case study of 15 patients with Zoon's balanitis, and emphasize the possible use of a carbon dioxide laser as an alternative therapy.
浆细胞性龟头炎是阴茎的一种慢性糜烂性病变。该病变对保守的局部治疗及一些手术治疗均难以奏效,且常需行包皮环切术作为一种治愈性措施。
1991年10月至2001年10月间,对15例临床及组织病理学诊断为浆细胞性龟头炎的患者进行了研究。其中5例接受了二氧化碳激光治疗。
患者年龄在36至69岁之间(平均50.8岁)。所有患者均未行包皮环切术,表现为龟头有分泌物及红斑性病变;10例患者的包皮龟头皱襞受累,8例患者的包皮内表面有病变。1例患者为人类免疫缺陷病毒阳性。5例接受了二氧化碳激光治疗。2例分别在1年和3年后复发,其余3例分别随访了2年、5年和6年,均未复发。1例患者发生了包皮硬化萎缩性苔藓。
我们展示了15例浆细胞性龟头炎患者的病例研究,并强调二氧化碳激光作为一种替代治疗方法的可能性。