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干燥闭塞性龟头炎:15例患者的病例报告,其中5例接受二氧化碳激光治疗。

Zoon's balanitis: presentation of 15 patients, five treated with a carbon dioxide laser.

作者信息

Retamar Roberto Adrián, Kien M C, Chouela E N

机构信息

Department of Dermatology, Hospital General de Agudos Dr Cosme Argerich, Buenos Aires, Argentina.

出版信息

Int J Dermatol. 2003 Apr;42(4):305-7. doi: 10.1046/j.1365-4362.2003.01304.x.

Abstract

BACKGROUND

Zoon's balanitis is a chronic erosive process of the penis. The lesions are refractory to conservative topical and some surgical therapy, and frequently require circumcision as a curative measure.

METHODS

Fifteen patients with a clinical and histopathologic diagnosis of Zoon's balanitis were studied between October 1991 and October 2001. Five were treated with a carbon dioxide laser.

RESULTS

The ages of the patients ranged from 36 to 69 years (average, 50.8 years). All the men were uncircumcised and presented with a discharge and erythematous lesions on the glans penis; the balanopreputial fold was affected in 10 patients and eight had a lesion on the internal surface of the prepuce. One patient was human immunodeficiency virus positive. Five were treated with a carbon dioxide laser. Two relapsed 1 and 3 years later, respectively, and the remaining three have been followed up for 2, 5, and 6 years, respectively, without relapse. One patient developed lichen sclerosus et atrophicus of the prepuce.

CONCLUSIONS

We have presented our case study of 15 patients with Zoon's balanitis, and emphasize the possible use of a carbon dioxide laser as an alternative therapy.

摘要

背景

浆细胞性龟头炎是阴茎的一种慢性糜烂性病变。该病变对保守的局部治疗及一些手术治疗均难以奏效,且常需行包皮环切术作为一种治愈性措施。

方法

1991年10月至2001年10月间,对15例临床及组织病理学诊断为浆细胞性龟头炎的患者进行了研究。其中5例接受了二氧化碳激光治疗。

结果

患者年龄在36至69岁之间(平均50.8岁)。所有患者均未行包皮环切术,表现为龟头有分泌物及红斑性病变;10例患者的包皮龟头皱襞受累,8例患者的包皮内表面有病变。1例患者为人类免疫缺陷病毒阳性。5例接受了二氧化碳激光治疗。2例分别在1年和3年后复发,其余3例分别随访了2年、5年和6年,均未复发。1例患者发生了包皮硬化萎缩性苔藓。

结论

我们展示了15例浆细胞性龟头炎患者的病例研究,并强调二氧化碳激光作为一种替代治疗方法的可能性。

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