Altmeyer P, Kastner U, Luther H
Dermatologische Klinik, Ruhr-Universität-Bochum (RUB).
Hautarzt. 1998 Jul;49(7):552-5. doi: 10.1007/s001050050787.
During the years 1985 up to 1995 53 patients between 18 and 80 years of age (mean age 54.7 years) with histologically and clinically proven Zoon's balanitis were treated by circumcision. The majority of patients had symptoms for more than 12 months. In five cases they had lasted for 8, 10, 16, 17 and 47 (!) years. 30 patients were investigated by means of physical examination and questionnaire in this retrospective study. Lesions involved glans in all patients, while in 17 of 30 patients both glans and prepuce were involved. None of the patients showed lesions of the prepuce only. In most cases Zoon's balanitis was successfully treated by circumcision in a period of two to four weeks. In four cases, psoriatic lesions, and in one case lichen ruber was diagnosed. In the remaining patient, whose circumcision was inadequate, a small area of balanitis persisted in the sulcus coronarius still covered by the foreskin. The curative effect of adequate circumcision in 100% of patients suggests that Zoon's balanitis is a relatively non-specific reactive balanitis caused by a disturbed "preputial-ecology". It is remarkable that other distinct inflammatory diseases of glans and prepuce can show features which are identical to those Zoon's balanitis.
在1985年至1995年期间，对53例年龄在18岁至80岁之间（平均年龄54.7岁）、经组织学和临床证实患有浆细胞性龟头炎的患者实施了包皮环切术治疗。大多数患者的症状持续超过12个月。其中5例患者的症状持续了8年、10年、16年、17年和47年（！）。在这项回顾性研究中，对30例患者进行了体格检查和问卷调查。所有患者的龟头均有病变，而在30例患者中有17例龟头和包皮均有病变。没有患者仅表现为包皮病变。在大多数情况下，浆细胞性龟头炎通过包皮环切术在两到四周内成功治愈。4例患者被诊断为银屑病病变，1例患者被诊断为红色扁平苔藓。在其余1例患者中，由于包皮环切术不彻底，冠状沟仍被包皮覆盖的部位仍有一小片龟头炎持续存在。100%的患者经充分包皮环切术后的疗效表明，浆细胞性龟头炎是一种由“包皮生态”紊乱引起的相对非特异性反应性龟头炎。值得注意的是，龟头和包皮的其他明显炎症性疾病可能表现出与浆细胞性龟头炎相同的特征。
