Remy-Jardin Martine, Amara Assia, Campistron Philippe, Mastora Ioana, Delannoy Valérie, Duhamel Alain, Remy Jacques
Department of Radiology, Hospital Calmette, University Center of Lille, Boulevard Jules Leclerc, 59037, Lille Cedex, France.
Eur Radiol. 2003 May;13(5):1165-71. doi: 10.1007/s00330-003-1821-z. Epub 2003 Feb 11.
The aim of this study was to evaluate the accuracy of 3-mm-thick reconstructed sections in the diagnosis of bronchiectasis with multislice CT (MSCT). Forty consecutive patients suspected of bronchiectasis (23 females, 17 males; mean age 51 years) underwent MSCT of the entire thorax with a 4x1-mm collimation (120 kV, 0.5 s/rotation, 80 mAs/slice) and a pitch of 1.75. From each data set (mean z-axis coverage: 257 mm; mean duration: 21 s), two series of images were systematically generated: 1-mm (group 1) and 3-mm (group 2)-thick reconstructed scans. Both series of images were obtained at 10-mm intervals and reconstructed with a high-spatial-frequency algorithm. Two observers independently analyzed the presence of bronchiectasis and associated abnormalities in group-1 and group-2 lung images. No significant difference between group 1 and group 2 was found in: (a) the detection of bronchiectasis, identified in 24 patients (60%) in group 1 and in 23 patients (57.5%) in group 2 ( p=0.08); (b) the evaluation of the extent of bronchiectasis, identifying focal bronchiectasis in 10 patients (25%) in group 1 and 7 patients (17.5%) in group 2 ( p=0.39) and multifocal bronchiectasis in 16 patients (40%) in both groups; (c) the characterisation of bronchiectasis (cylindral bronchiectasis: group 1, n=24, 60%; group 2, n=21, 53%, p=0.08); varicose bronchiectasis: group 1, n=5, 12.5%; group 2, n=6, 15%, p=0.56); and cystic bronchiectasis: group 1, n=2, 5%; group 2, n=2, 5%). Apart from the identification of abnormal bronchial wall thickening (group 2, n=35, 87.5%, vs group 1, n=31, 77.5%, p<0.05), recognition of associated bronchopulmonary anomalies did not differ between the two groups. This study demonstrates a comparable accuracy of the 3- and 1-mm-thick reconstructed scans in the detection and characterization of bronchiectasis. These results suggest the potential usefulness of 3-mm-thick scans generated from 4x2.5-mm acquisitions in the screening of bronchiectasis, which would allow a 20% radiation dose reduction compared with the present investigation.
本研究的目的是评估多层螺旋CT（MSCT）中3毫米厚的重建图像在支气管扩张诊断中的准确性。连续40例疑似支气管扩张的患者（23例女性，17例男性；平均年龄51岁）接受了全胸MSCT检查，扫描参数为4×1毫米准直（120 kV，0.5秒/旋转，80 mAs/层），螺距为1.75。从每个数据集（平均z轴覆盖范围：257毫米；平均扫描时间：21秒）中，系统地生成了两组图像：1毫米厚（第1组）和3毫米厚（第2组）的重建扫描图像。两组图像均以10毫米间隔获取，并采用高空间频率算法进行重建。两名观察者独立分析第1组和第2组肺图像中支气管扩张及相关异常情况。在以下方面，第1组和第2组之间未发现显著差异：（a）支气管扩张的检出率，第1组24例（60%），第2组23例（57.5%）（p = 0.08）；（b）支气管扩张范围的评估，第1组10例（25%）为局灶性支气管扩张，第2组7例（17.5%）为局灶性支气管扩张（p = 0.39），两组均有16例（40%）为多灶性支气管扩张；（c）支气管扩张的特征（柱状支气管扩张：第1组，n = 24，60%；第2组，n = 21，53%，p = 0.08）；静脉曲张型支气管扩张：第1组，n = 5，12.5%；第2组，n = 6，15%，p = 0.56）；囊状支气管扩张：第1组，n = 2，5%；第2组，n = 2，5%）。除了识别异常支气管壁增厚外（第2组，n = 35，87.5%，第1组，n = 31，77.5%，p < 0.05），两组在识别相关支气管肺异常方面无差异。本研究表明，在支气管扩张的检测和特征描述方面，3毫米厚和1毫米厚的重建扫描图像具有相当的准确性。这些结果提示，从4×2.5毫米采集数据生成的3毫米厚扫描图像在支气管扩张筛查中可能有用，与本研究相比，可减少20%的辐射剂量。
