Kim J S, Müller N L, Park C S, Grenier P, Herold C J
Department of Radiology, Vancouver Hospital and Health Sciences Centre, B.C., Canada.
AJR Am J Roentgenol. 1997 Mar;168(3):751-4. doi: 10.2214/ajr.168.3.9057529.
The aim of this study was to determine the frequency of diagnostic findings of bronchiectasis on thin-section CT and the usefulness of those findings in distinguishing patients with cylindrical bronchiectasis from healthy subjects.
The study was retrospective and included 26 healthy adults, 10 consecutive patients with surgically proven cylindrical bronchiectasis, and 49 patients who had been prospectively diagnosed at three institutions as having cylindrical bronchiectasis. All patients had 1.0- to 1.5-mm-collimation CT scans obtained at 10-mm intervals through the chest. The CT scans were independently reviewed in random order by two chest radiologists.
Findings in patients with bronchiectasis that were not seen by either observer in any of the healthy subjects included visualization of a bronchus within 1 cm of the costal pleura and visualization of a bronchus abutting the mediastinal pleura. The two observers saw these findings on 96 (81%) and 63 (53%) of 118 CT scans in the 59 patients with bronchiectasis, respectively. Lack of tapering of bronchi was seen in five (10%) of 52 reviews in healthy subjects compared with 95% of reviews in patients with bronchiectasis. Bronchoarterial ratios greater than 1 were identified in 11 (21%) of 52 reviews in healthy subjects compared with 95% of reviews in patients with bronchiectasis. We calculated good agreement between the two observers (kappa values equal to or greater than .63).
In most cases, thin-section CT allows reliable distinction of patients with cylindrical bronchiectasis from healthy subjects.
本研究旨在确定薄层CT上支气管扩张的诊断发现频率,以及这些发现对于区分圆柱状支气管扩张患者与健康受试者的有用性。
本研究为回顾性研究,纳入26名健康成年人、10名经手术证实为圆柱状支气管扩张的连续患者,以及49名在三家机构前瞻性诊断为圆柱状支气管扩张的患者。所有患者均进行了层厚1.0至1.5毫米、层间距10毫米的胸部CT扫描。两名胸部放射科医生以随机顺序独立回顾这些CT扫描图像。
支气管扩张患者中出现的、在任何健康受试者中均未被任何一名观察者发现的表现包括肋胸膜1厘米范围内支气管的显影以及与纵隔胸膜相邻支气管的显影。在59例支气管扩张患者的118次CT扫描中,两名观察者分别在96次(81%)和63次(53%)扫描中观察到了这些表现。健康受试者的52次回顾中有5次(10%)观察到支气管无逐渐变细,而支气管扩张患者的回顾中这一比例为95%。健康受试者的52次回顾中有11次(21%)观察到支气管动脉比大于1,而支气管扩张患者的回顾中这一比例为95%。我们计算出两名观察者之间具有良好的一致性(kappa值等于或大于0.63)。
在大多数情况下,薄层CT能够可靠地区分圆柱状支气管扩张患者与健康受试者。