Rawlinson William D, Waliuzzaman Zubair, Carter Ian W, Belessis Yvonne C, Gilbert Katarnya M, Morton John R
Virology Division, Department of Microbiology, South Eastern Area Laboratory Services, Prince of Wales Hospital, Randwick, New South Wales, Australia.
J Infect Dis. 2003 Apr 15;187(8):1314-8. doi: 10.1086/368411. Epub 2003 Mar 26.
Children with asthma were studied during the Southern hemisphere winter and summer of 2001-2002. Human rhinovirus (hRV) was significantly associated (P=.0001) with asthma exacerbations in winter and spring/summer, but not in intervening asymptomatic periods. Although hRV was also found in children with upper respiratory tract infection (URTI) who underwent sampling at the same time, it was present in significantly higher numbers of children with symptomatic asthma (P<.0001). Human metapneumovirus was also found in small numbers of children with URTI, but significantly less frequently in children with asthma.
在2001 - 2002年南半球的冬季和夏季对哮喘儿童进行了研究。人鼻病毒（hRV）与冬季和春/夏季的哮喘加重显著相关（P = 0.0001），但在无症状的间隔期则不然。虽然在同时进行采样的上呼吸道感染（URTI）儿童中也发现了hRV，但有症状哮喘儿童中的hRV数量明显更多（P < 0.0001）。在少数URTI儿童中也发现了人偏肺病毒，但在哮喘儿童中出现的频率明显较低。
