单肾大鼠摄入N-4-(4'-氟联苯)乙酰胺后肾细胞癌发病率降低。
Decreased incidence of renal cell carcinoma in rats with one kidney ingesting N-4-(4'-fluorobiphenyl)acetamide.
作者信息
Reuber M D
出版信息
Experientia. 1976 Feb 15;32(2):218-9. doi: 10.1007/BF01937775.
PMID:1269618
Abstract
Buffalo strain male rats, 12 weeks of age, ingesting 0.04% N-4-(4'-fluorobiphenyl)acetamide in a semisynthetic diet with both kidneys intact were more susceptible to the development of hyperplasia and carcinomas of the kidney than were rats with a uninephrectomy.
摘要
12周龄的雄性布法罗品系大鼠，在双肾完整的情况下，食用含0.04% N-4-(4'-氟联苯)乙酰胺的半合成饲料，比单侧肾切除的大鼠更易发生肾脏增生和癌变。
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