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三碘甲状腺丙酸在乙醇 - 盐酸中的核磁共振研究。

NMR-studies of triiodothyropropionic acid in ethanol-HCl.

作者信息

Mazzocchi P H, Ammon H L, Colicelli E, Hohokabe Y, Cody V

出版信息

Experientia. 1976 Apr 15;32(4):419-20. doi: 10.1007/BF01920770.

DOI:10.1007/BF01920770
PMID:1269638
Abstract

The barrier to rotation in the N-acetyl methyl ester of the thyroxine was found to be 8.6 kcal mol-1. Previous experiments determining the barrier to rotation in triiodothyropropionic acid in HCl-ethanol were shown to be in error.

摘要

已发现甲状腺素的N - 乙酰甲酯中旋转位垒为8.6千卡/摩尔。先前在盐酸 - 乙醇中测定三碘甲状腺丙酸旋转位垒的实验已证明是错误的。

相似文献

1
NMR-studies of triiodothyropropionic acid in ethanol-HCl.三碘甲状腺丙酸在乙醇 - 盐酸中的核磁共振研究。
Experientia. 1976 Apr 15;32(4):419-20. doi: 10.1007/BF01920770.
2
Thyroid hormone structure: molecular conformation of triiodothyropropionic acid.甲状腺激素结构：三碘甲状腺丙酸的分子构象
Biochem Biophys Res Commun. 1972 Sep 26;48(6):1433-6. doi: 10.1016/0006-291x(72)90873-x.
3
Metabolic pathways of tetraiodothyroacetic acid, triidothyroacetic acid, tetraiodothyropropionic acid and triiodothyropropionic acid.四碘甲状腺乙酸、三碘甲状腺乙酸、四碘甲状腺丙酸和三碘甲状腺丙酸的代谢途径。
Biochem Pharmacol. 1962 Jul;11:627-37. doi: 10.1016/0006-2952(62)90124-7.
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The effect of thyroxine, tetraiodothyroacetic acid, triiodothyronine, triiodothyroacetic acid, triiodothyropropionic acid, diiodothyronine, thyronine and pyrogen lipopolysaccharide on corticosterone secretion in the rat.
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1H and 13C NMR relaxation studies of molecular dynamics of the thyroid hormones thyroxine, 3,5,3'-triiodothyronine, and 3,5-diiodothyronine.甲状腺激素甲状腺素、3,5,3'-三碘甲状腺原氨酸和3,5-二碘甲状腺原氨酸分子动力学的1H和13C NMR弛豫研究。
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本文引用的文献

1
Thyroxine analogues. III. Antigoitrogenic and calorigenic activity of some alkyl substituted analogues of thyroxine.甲状腺素类似物。III. 某些甲状腺素烷基取代类似物的抗甲状腺肿和产热活性。
J Biol Chem. 1960 Jun;235:1732-7.
2
Thyroxine analogues. VII. Antigoitrogenic, calorigenic, and hypocholesteremic activities of some aliphatic, alicyclic, and aromatic ethers of 3, 5-diiodoty-rosine in the rat.甲状腺素类似物。VII. 大鼠体内3,5-二碘酪氨酸的一些脂肪族、脂环族和芳香族醚的抗甲状腺肿、产热及降胆固醇活性
J Biol Chem. 1962 Dec;237:3832-8.
3
Thyroid hormone structure: molecular conformation of triiodothyropropionic acid.
甲状腺激素结构：三碘甲状腺丙酸的分子构象
Biochem Biophys Res Commun. 1972 Sep 26;48(6):1433-6. doi: 10.1016/0006-291x(72)90873-x.
4
Triiodothyronine: the 3'iodine is proximal to the -ring in crystal structure conformation.三碘甲状腺原氨酸：在晶体结构构象中，3'位碘靠近苯环。
Science. 1972 Feb 18;175(4023):764-6. doi: 10.1126/science.175.4023.764.
5
Distal conformation of thyroid hormones. The crystal structure of 3,5,3'-triiodothyroacetic acid H-diethanolamine (1:1) complex.甲状腺激素的远端构象。3,5,3'-三碘甲状腺乙酸H-二乙醇胺（1:1）复合物的晶体结构。
Biochem Biophys Res Commun. 1973 May 15;52(2):430-3. doi: 10.1016/0006-291x(73)90729-8.
6
Thyroid hormone structure: molecular conformation of 3'-isopropyl-3,5-diiodo-L-thyronine, the most potent known thyromimetic agent.甲状腺激素结构：3'-异丙基-3,5-二碘-L-甲状腺原氨酸的分子构象，一种已知最有效的拟甲状腺剂。
Biochem Biophys Res Commun. 1973 May 15;52(2):407-12. doi: 10.1016/0006-291x(73)90726-2.
7
Crystal structure and molecular conformation of the thyroid hormone distal 3,5,3'-triiodo-L-thyronine.甲状腺激素远端3,5,3'-三碘-L-甲状腺原氨酸的晶体结构和分子构象
J Am Chem Soc. 1974 Oct 16;96(21):6720-5. doi: 10.1021/ja00828a030.
8
Confromation of thyroid hormone analogues.
Nature. 1975 Sep 25;257(5524):334-6. doi: 10.1038/257334a0.
9
Distal conformation of thyroid hormones. Crystal and molecular structure of 3,5,3'-triiodo-L-thyronine methyl ester.甲状腺激素的远端构象。3,5,3'-三碘-L-甲状腺原氨酸甲酯的晶体结构和分子结构。
J Med Chem. 1975 Feb;18(2):126-9. doi: 10.1021/jm00236a002.
10
Thyroid hormone conformation from NMR studies of triiodothropropionic acid.
Nature. 1975 Jan 3;253(5486):50-1. doi: 10.1038/253050a0.