Hayes C J, Palmer J D
Experientia. 1976 Apr 15;32(4):469-70. doi: 10.1007/BF01920801.
The spontaneous locomotor activity of the laboratory mouse is significantly depressed by the ingestion of deuterium oxide. The response, which is reversible, is a retilinear one with up to 70% reduction in activity with the administration of 25% heavy water.