血清素拮抗剂及一种新型三环化合物对大鼠排卵的抑制作用
Inhibition of ovulation in rats by antagonists to serotonin and by a new tricyclic compound.
作者信息
Markó M, Flückiger E
出版信息
Experientia. 1976 Apr 15;32(4):491-2. doi: 10.1007/BF01920815.
PMID:1269657
Abstract
The ovulation inhibiting activity in adult rats of the 5HT-antagonists cyproheptadine, mianserin and methysergide is shown. Furthermore the activity of a newly synthetized Cycloheptathiophenederivative, compound 26-921, which inhibits LH-secretion and consequently ovulation, is described.
摘要
已表明5-羟色胺拮抗剂赛庚啶、米安色林和甲基麦角新碱在成年大鼠中的排卵抑制活性。此外，还描述了一种新合成的环庚噻吩衍生物（化合物26 - 921）的活性，该衍生物可抑制促黄体生成素分泌并因此抑制排卵。
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