Zu Rong-qiang, Wu Yang-sheng, Zhu Feng-cai, Liu Guang-zhong
Jiangsu Province Center for Disease Prevention and Control, Nanjing 210009, China.
Zhonghua Liu Xing Bing Xue Za Zhi. 2003 Feb;24(2):109-12.
To analyze the incidence rate, animal hosts, and human inapparent infection rate from surveillance data collected in Jiangsu province from 1996 to 2000 and the risk factors of hemorrhagic fever with renal syndrome (HFRS).
Data on the incidence rate was collected from the whole province to describe the epidemiologic characteristics of HFRS. Data on the density of rats, proportion of rats with virus, index of rats with virus and the human inapparent infection rate were collected in special areas according to the standardised protocol in the project.
The incidence rate of HFRS reduced continuously in Jiangsu province, with a 42.17% reduction from 1996 to 2000. The ratio between the incidence rate of autumn-winter peak and spring peak had also reduced. The main host in spring was Rattus norvegicus (with a density of 3.07%), while that in autumn was Apodemus agrarius (with a density of 4.64%). The density of main hosts and mixed species of rats had all reduced during the five years of observation. The proportions of Rattus norvegicus, Apodemus agrarius, Mus musculus with virus were relatively high in spring and autumn. The index of Rattus norvegicus and Mus musculus with virus in spring were 0.025 5 and 0.028 4 respectively, while that of Apodemus agrarius with virus in autumn was 0.030 2. The average human inapparent infection rate was 4.73% in the five years.
The incidence rate of HFRS in Jiangsu reduced significantly from 1996 to 2000, but the risk factors still widely existed. Suggesting that the surveillance program needs to be carried out steadily in Jiangsu.
分析1996年至2000年江苏省监测数据中肾综合征出血热(HFRS)的发病率、动物宿主及人群隐性感染率,并分析其危险因素。
收集全省发病率数据以描述HFRS的流行病学特征。按照项目标准化方案,在特定地区收集鼠密度、带病毒鼠比例、带病毒鼠指数及人群隐性感染率数据。
江苏省HFRS发病率持续下降,1996年至2000年下降了42.17%。秋冬季发病高峰与春季发病高峰的发病率之比也有所下降。春季主要宿主为褐家鼠(密度为3.07%),秋季为黑线姬鼠(密度为4.64%)。在五年观察期内,主要宿主及鼠类混合种群的密度均有所下降。春季和秋季褐家鼠、黑线姬鼠、小家鼠带病毒的比例相对较高。春季褐家鼠和小家鼠的带病毒指数分别为0.025 5和0.028 4,秋季黑线姬鼠的带病毒指数为0.030 2。五年间人群平均隐性感染率为4.73%。
1996年至2000年江苏省HFRS发病率显著下降,但危险因素仍然广泛存在。提示江苏省仍需稳步开展监测工作。