Huang Li-Yong, Zhou Hang, Yin Wen-Wu, Wang Qin, Sun Hui, Ding Fan, Man Teng-Fei, Li Qun, Feng Zi-Jian
Office for Disease Control and Prevention, Beijing, China.
Zhonghua Liu Xing Bing Xue Za Zhi. 2012 Jul;33(7):685-91.
To analyze the surveillance data on hemorrhagic fever with renal syndrome (HFRS) including the epidemiological characteristics and trend of the disease, in 2010.
Descriptive methods were conducted to analyze the surveillance data in 2010 which were collected from the internet-based National Notifiable Disease Reporting System and 40 HFRS sentinels in China.
There were 9526 cases of HFRS reported in 2010 in the country with an annual morbidity of 0.71/10(5), which was higher than that reported in 2009. And the case fatality rate in 2010 was 1.24%. During the year 2010, most cases were reported in spring and autumn-winter season, with November as the peak month. The proportion of cases reported in autumn-winter season was higher than that in spring. The number of cases reported in males was higher than that in females among all the age groups, and similar pattern of mortality could be seen in most of the age groups. The percentage of cases over 60 years old had increased in recent years. Farmers were still under the highest risk. Density and the virus-carrying rate of animal hosts, as well as the infection rate were relatively stable and similar to the previous findings. As to the prevailing species, Apodemus agrarius and Rattus norvegicus were still the most common and leading animal hosts. However, the dominant species in sentinel of Yunnan were Rattus flavipectus and Eothenomys miletus respectively, and a new hantavirus called LUXV was found, namely Eothenomys miletus.
HFRS cases were widely distributed in most provinces of China, but cases mainly focus on certain areas and present the nature of aggregation. The risk of outbreak could not be ruled out for variety of factors. Population characteristics and seasonal fluctuation had been changing.
分析2010年肾综合征出血热（HFRS）监测数据，了解该病的流行病学特征及流行趋势。
采用描述性方法分析2010年从基于网络的国家法定传染病报告系统及中国40个HFRS监测点收集的监测数据。
2010年全国共报告HFRS病例9526例，年发病率为0.71/10万，高于2009年报告发病率。2010年病死率为1.24%。2010年发病以春、秋冬季为主，11月为发病高峰月。秋冬季报告病例数占比高于春季。各年龄组男性报告病例数均高于女性，多数年龄组死亡情况类似。近年来60岁以上病例占比有所增加。农民仍是高危人群。动物宿主密度、带病毒率及感染率相对稳定，与既往结果相似。优势宿主种类仍为黑线姬鼠和褐家鼠。但云南监测点优势宿主分别为黄胸鼠和大绒鼠，且发现一种新型汉坦病毒，即大绒鼠汉坦病毒（LUXV）。
HFRS病例在中国多数省份广泛分布，但主要集中在某些地区，呈现聚集性。因多种因素，不能排除暴发风险。人群特征及季节性波动一直在变化。
