Schefft Bruce K, Testa S Marc, Dulay Mario F, Privitera Michael D, Yeh Hwa-Shain
Department of Psychology, University of Cincinnati, Cincinnati, OH 45221, USA.
Epilepsy Behav. 2003 Apr;4(2):161-8. doi: 10.1016/s1525-5050(03)00026-x.
The present study examined the diagnostic utility of confrontation naming tasks and phonemic paraphasia production in lateralizing the epileptogenic region in patients with temporal lobe epilepsy (TLE). Further, the role of intelligence in moderating the diagnostic utility of confrontation naming tasks was assessed. Eighty patients with medically intractable complex partial seizures (40 left TLE, 40 right TLE) received the Boston Naming Test (BNT) and the Visual Naming subtest (VNT) of the Multilingual Aphasia Examination. The BNT was diagnostically more sensitive than the VNT in identifying left TLE (77.5% vs 17.5%, respectively). The utility of BNT performance and paraphasias was maximal in patients with Full Scale IQs >or=90 who were 6.8 times more likely to have left TLE than patients without paraphasias. Preoperative assessment of confrontation naming ability and phonemic paraphasia production using the BNT provided diagnostically useful information in lateralizing the epileptogenic region in left TLE.
本研究考察了对命名任务和音素性错语产生在颞叶癫痫（TLE）患者癫痫源区定位中的诊断效用。此外，还评估了智力在调节对命名任务诊断效用中的作用。80例药物难治性复杂部分性发作患者（40例左侧TLE，40例右侧TLE）接受了波士顿命名测试（BNT）和多语言失语症检查的视觉命名子测试（VNT）。在识别左侧TLE方面，BNT的诊断敏感性高于VNT（分别为77.5%和17.5%）。对于全量表智商≥90的患者，BNT表现和错语的效用最大，这类患者患左侧TLE的可能性是无错语患者的6.8倍。术前使用BNT评估对命名能力和音素性错语产生，为左侧TLE癫痫源区定位提供了有诊断价值的信息。
