O'Connor F A, Buchanan K D, Connon J J, Shahidullah M
Diabetologia. 1976 May;12(2):145-8. doi: 10.1007/BF00428980.
Immunoreactive secretin (IRS) and immunoreactive insulin (IRI) levels were measured in humans and dogs following the intraduodenal instillation of hydrochloric acid. IRS levels rose after acid in both instances, but a concomitant rise in peripheral IRI levels was not noted. Premedication of the humans with Scopolamine prevented a rise of IRS in the human subjects. It is concluded that the endovenous release of IRS alone does not result in increased IRI levels in peripheral blood and that IRS release may be under vagal control.
在向人和狗十二指肠内滴注盐酸后，测量了免疫反应性促胰液素（IRS）和免疫反应性胰岛素（IRI）水平。在这两种情况下，酸刺激后IRS水平均升高，但未观察到外周IRI水平随之升高。用东莨菪碱对人进行预处理可防止人体受试者IRS升高。得出的结论是，仅IRS的静脉内释放不会导致外周血中IRI水平升高，并且IRS的释放可能受迷走神经控制。
