Suppr超能文献

爱沙尼亚中年女性人群中的动脉高血压、左心室几何形态与QT离散度

Arterial hypertension, left ventricular geometry and QT dispersion in a middle-aged Estonian female population.

作者信息

Shipilova Tatjana, Pshenichnikov Igor, Kaik Jüri, Volozh Olga, Abina Jelena, Kalev Maie, Lass Jaanus, Karai Denis

机构信息

Department of Clinical Cardiology of Estonian Institute of Cardiology, Tallinn, Estonia.

出版信息

Blood Press. 2003;12(1):12-8.

Abstract

The aim of the present study was to determine the prevalence of Left ventricular hypertrophy (LVH) and different left ventricular (LV) geometric patterns in the middle-aged women population of Tallinn, to assess the relationship between LV geometry, age, blood pressure and LV repolarization duration and inhomogeneity. A random sample of the population, 482 women aged 35-59, was examined in the framework of a cardiovascular risk factors survey for the WHO/CINDI programme years 1999-2000. Patients with valvular pathology, primary cardiomyopathy, atrial fibrillation, bundle branch blocks and flat T wave on electrocardiography (ECG) were excluded; 398 (82.2%) of the participants underwent echocardiography (Echo) and standard 12-lead ECG at rest and were included in the study. LVH was defined if left ventricular mass (LVM), LVM/height and LVM/BSA were >198 g, >121 g/m and > 120 g/m2, respectively. Arterial hypertension was determined in 23.1% of the women. The prevalence of arterial hypertension was three times higher in those aged 50-59 than in those aged 40-49 (37.4% vs 13.2%; p < 0.05). Different geometric patterns were found as follows: concentric hypertrophy in 9.1%; eccentric hypertrophy 33.9%; concentric remodelling 9.5% and normal geometry 47.5% of the participants. Concentric hypertrophy was found exclusively in hypertensive women and increased with age. No age-related eccentric hypertrophy and concentric remodelling differences were found, either in the normotensive or in the hypertensive group. Prolonged QT dispersion--a marker of increased myocardial electrical instability, was associated with LVH and arterial hypertension and was related mostly to concentric hypertrophy in hypertensives.

摘要

本研究的目的是确定塔林中年女性人群中左心室肥厚(LVH)的患病率及不同的左心室(LV)几何形态,评估LV几何形态、年龄、血压与LV复极持续时间及不均一性之间的关系。在1999 - 2000年WHO/CINDI项目心血管危险因素调查框架内,对482名年龄在35 - 59岁的女性人群进行了随机抽样检查。排除患有瓣膜病变、原发性心肌病、心房颤动、束支传导阻滞以及心电图(ECG)上T波平坦的患者;398名(82.2%)参与者接受了静息状态下的超声心动图(Echo)检查和标准12导联ECG检查,并纳入研究。若左心室质量(LVM)、LVM/身高和LVM/体表面积分别>198 g、>121 g/m和>120 g/m²,则定义为LVH。23.1%的女性被诊断为动脉高血压。50 - 59岁女性的动脉高血压患病率比40 - 49岁女性高两倍(37.4%对13.2%;p<0.05)。发现了不同的几何形态如下:向心性肥厚占9.1%;离心性肥厚占33.9%;向心性重构占9.5%;正常几何形态占47.5%。向心性肥厚仅在高血压女性中发现,且随年龄增加。在正常血压组或高血压组中,均未发现与年龄相关的离心性肥厚和向心性重构差异。QT离散度延长——心肌电不稳定性增加的一个指标,与LVH和动脉高血压相关,且在高血压患者中主要与向心性肥厚有关。

文献AI研究员

20分钟写一篇综述,助力文献阅读效率提升50倍。

立即体验

用中文搜PubMed

大模型驱动的PubMed中文搜索引擎

马上搜索

文档翻译

学术文献翻译模型,支持多种主流文档格式。

立即体验