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[组织工程在再生医学临床实践中的意义]

[Significance of tissue engineering in clinical practice of regenerative medicine].

作者信息

Tabata Yasuhiko

机构信息

Department of Biomaterials, Field of Tissue Engineering, Institute for Frontier Medical Sciences, Kyoto University.

出版信息

Nihon Rinsho. 2003 Mar;61(3):411-6.

PMID:12701166
Abstract

It is undoubtedly important for regenerative medicine to discover and use the cells of high proliferation and differentiation potentials. However, there are numerous cases where the tissue regeneration cannot be always achieved only by using the cells. Thus, an environmental site suitable for enabling cells to induce tissue regeneration is highly required for successful tissue regeneration. Tissue engineering is the biomedical technology or methodology indispensable to create this regeneration site while it makes use of the scaffold for cell proliferation and differentiation, the drug delivery system of biological signals, and their combination with cells. This paper describes the present status and research data of tissue engineering to emphasize the considerable significance in regenerative medicine.

摘要

发现并利用具有高增殖和分化潜能的细胞对于再生医学无疑是重要的。然而,在许多情况下,仅使用细胞并不能总是实现组织再生。因此,成功的组织再生非常需要一个适合使细胞诱导组织再生的环境位点。组织工程是一种生物医学技术或方法,它在利用用于细胞增殖和分化的支架、生物信号的药物递送系统以及它们与细胞的组合来创建这个再生位点方面是不可或缺的。本文描述了组织工程的现状和研究数据,以强调其在再生医学中的重大意义。

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