Ross Phillip L, Littenberg Benjamin, Fearn Paul, Scardino Peter T, Karakiewicz Pierre I, Kattan Michael W
Department of Urology, Memorial Sloan-Kettering Cancer Center, New York, NY 10021, USA.
Int J Technol Assess Health Care. 2003 Winter;19(1):135-47. doi: 10.1017/s0266462303000138.
To develop and validate a paper-based instrument that is simple to administer and produces a reliable estimate of patient standard gamble (SG) utilities for current health status.
A 1-page paper questionnaire instrument, paper standard gamble (PSG), was designed to estimate SG utilities. We performed two studies to assess the validity of PSG. First we compared PSG and SG utilities for current health in patients with prostate cancer. They randomly received either PSG followed by SG or vice versa, always with an intervening SF-12. In the second validity study, we assessed the test-retest reliability of PSG by administering it to prostate cancer patients twice, at least 2 weeks apart.
In the first study, utilities were assessed in 64 men (32 per SG/PSG order group). A paired-comparison t test suggested no difference between SG and PSG (mean difference = -0.007; 95% confidence interval (Cl), -0.022 to 0.008). The concordance correlation coefficient was 0.92 (95% Cl, 0.79 to 0.99). In the second study, test and retest PSGs were available for 184 patients. The concordance correlation coefficient was 0.88 (95% Cl, 0.73 to 0.94).
These data suggest that PSG may serve as a reliable substitute for SG when current health utility is of interest. PSG may have particular advantages for acquisition of health-related quality-of-life data in longitudinal studies.
开发并验证一种纸质工具，该工具易于实施，能够对患者当前健康状况的标准博弈（SG）效用值进行可靠估计。
设计了一份1页的纸质问卷工具——纸质标准博弈（PSG），用于估计SG效用值。我们进行了两项研究以评估PSG的有效性。首先，我们比较了前列腺癌患者当前健康状况下PSG和SG的效用值。他们随机接受先PSG后SG或先SG后PSG的测试，中间均插入一份SF - 12问卷。在第二项有效性研究中，我们通过对前列腺癌患者至少间隔2周进行两次PSG测试，评估了PSG的重测信度。
在第一项研究中，对64名男性（每个SG/PSG测试顺序组32名）进行了效用值评估。配对比较t检验表明SG和PSG之间无差异（平均差异 = -0.007；95%置信区间（Cl），-0.022至0.008）。一致性相关系数为0.92（95% Cl，0.79至0.99）。在第二项研究中，有184名患者的PSG测试和重测数据。一致性相关系数为0.88（95% Cl，0.73至0.94）。
这些数据表明，当关注当前健康效用时，PSG可作为SG的可靠替代方法。在纵向研究中获取健康相关生活质量数据方面，PSG可能具有特别的优势。
