Joy Diamond, Thava Vallipuram R, Scott Brian B
Department of Gastroenterology, Lincoln County Hospital, UK.
Eur J Gastroenterol Hepatol. 2003 May;15(5):539-43. doi: 10.1097/01.meg.0000059112.41030.2e.
Non-alcoholic fatty liver disease is increasingly being recognized as an important and common condition, affecting approximately 20% of the general population. Although liver biopsy is currently the gold standard for diagnosis, there is a need for less invasive methods. Imaging by ultrasound, computerized tomography and magnetic resonance are all able to demonstrate fat. In this paper, these three imaging techniques are critically assessed. Ultrasound, although probably not the most reliable imaging method, has many advantages and, when positive, gives a high degree of certainty of the diagnosis depending on the prevalence of fatty liver in the population being studied. Unlike liver biopsy, none of these techniques is able to differentiate simple steatosis from non-alcoholic steatohepatitis.
非酒精性脂肪性肝病日益被视为一种重要且常见的病症，影响着约20%的普通人群。尽管肝活检目前是诊断的金标准，但仍需要侵入性较小的方法。超声、计算机断层扫描和磁共振成像均能够显示脂肪。本文对这三种成像技术进行了批判性评估。超声虽然可能不是最可靠的成像方法，但具有许多优点，并且在呈阳性时，根据所研究人群中脂肪肝的患病率，能给出高度确定的诊断。与肝活检不同，这些技术均无法区分单纯性脂肪变性和非酒精性脂肪性肝炎。
