Nitroxyl gets to the heart of the matter.
作者信息
Feelisch Martin
机构信息
Louisiana State University Health Sciences Center, Department of Molecular and Cellular Physiology, 1501 Kings Highway, Shreveport, LA 71130, USA.
出版信息
Proc Natl Acad Sci U S A. 2003 Apr 29;100(9):4978-80. doi: 10.1073/pnas.1031571100. Epub 2003 Apr 18.
Abstract
摘要
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2
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3
Treatment of heart failure through stabilization of the cardiac ryanodine receptor.
Circulation. 2003 Jan 28;107(3):378-80. doi: 10.1161/01.cir.0000046342.46135.cb.
4
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