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C5b-9复合物:经典途径和替代途径产生的复合物的亚基组成。

The C5b-9 complex: subunit composition of the classical and alternative pathway-generated complex.

作者信息

Podack E R, Kolb W P, Muller-Eberhard H J

出版信息

J Immunol. 1976 May;116(5):1431-4.

PMID:1270802
Abstract

The membrane attack complex of complement (C5b-9) is identical in composition regardless of which pathway of activation was instrumental in its formation. Band V protein was consistently a subunit of the soluble complex. Since band V protein is not required for complement-dependent cytolysis, it probably represents a membrane site equivalent in serum of the nascent C5b-9 complex.

摘要

补体的膜攻击复合物(C5b-9),无论其通过何种激活途径形成,其组成都是相同的。V带蛋白始终是可溶性复合物的一个亚基。由于补体依赖性细胞溶解并不需要V带蛋白,它可能代表新生C5b-9复合物在血清中的一个膜位点等同物。

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The C5b-9 complex: subunit composition of the classical and alternative pathway-generated complex.C5b-9复合物:经典途径和替代途径产生的复合物的亚基组成。
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J Exp Med. 1981 Sep 1;154(3):763-77. doi: 10.1084/jem.154.3.763.
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J Clin Invest. 1983 Aug;72(2):560-73. doi: 10.1172/JCI111004.
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Terminal complement complex in plasma from patients with systemic lupus erythematosus and other glomerular diseases.系统性红斑狼疮及其他肾小球疾病患者血浆中的终末补体复合物。
Clin Exp Immunol. 1987 Nov;70(2):417-24.
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