[蜱传脑炎病毒感染的人RH细胞中干扰素诱导基因IFI-54k和IFI-56k的延迟激活]
[Late activation of interferon-induced genes IFI-54k and IFI-56k in human RH cells infected with tick-borne encephalitis virus].
作者信息
Gavrilov B G, Monastyrskaia G S, Velikodvorskaia T V, Filiukova O B, Konovalova S N, Kachko A A, Protopopova E V, Nikolaev L G, Loktev V B, Sverdlov E D
机构信息
Shemyakin-Ovchinnikov Institute of Bioorganic Chemistry, Russian Academy of Sciences, ul. Miklukho-Maklaya 16/10, GSP Moscow, 117997 Russia.
出版信息
Bioorg Khim. 2003 Mar-Apr;29(2):175-80. doi: 10.1023/a:1023260415910.
The genes that were induced and suppressed in human embryonic kidney cell line RH upon the infection with tick-borne encephalitis virus were studied by the method of subtractive hybridization. The expression of interferon-induced genes IFI-54K and IFI-56K in the infected cells was found to increase 50-100-fold.
采用消减杂交法研究了蜱传脑炎病毒感染人胚肾细胞系RH后诱导和抑制的基因。结果发现，感染细胞中干扰素诱导基因IFI-54K和IFI-56K的表达增加了50至100倍。
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