The interferon- and virus-inducible IFI-56K and IFI-54K genes are located on human chromosome 10 at bands q23-q24.

IFI-56K and IFI-54K are two human genes that are strongly induced by interferon and viruses. These genes are closely related at the protein, RNA, and promoter levels. By means of the somatic cell hybrid technique, the two genes have been previously located on chromosome 10. Using in situ hybridization, we show here that both IFI-54K and IFI-56K genes map to 10q23-q24. This result does not confirm the previous localization of the IFI-56K gene at the junction of the 10q25 and 10q26 bands.