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有和没有早期语言发育迟缓的高功能自闭症成年人的结局:对自闭症与阿斯伯格综合征鉴别诊断的启示

Outcome in high-functioning adults with autism with and without early language delays: implications for the differentiation between autism and Asperger syndrome.

作者信息

Howlin Patricia

机构信息

Department of Psychology, St. George's Hospital Medical School, Cranmer Terrace, London SW17 ORE, UK.

出版信息

J Autism Dev Disord. 2003 Feb;33(1):3-13. doi: 10.1023/a:1022270118899.

Abstract

The question of whether Asperger syndrome and high-functioning autism should be considered as the same or different conditions has been a source of debate and controversy over recent years. In the present study, 34 adults with autism who had shown early delays in language were compared with 42 individuals who were reported to have had no such delays, either in their use of words or phrases. All participants were at least 18 years of age, had a nonverbal IQ of 70 or above and met ADI-R criteria for age of onset, communication and social impairments, and stereotyped behaviors. Those in the language delay group were diagnosed as having high-functioning autism. The remainder were designated as having Asperger syndrome. The groups were matched for age, nonverbal IQ and gender. No significant differences were found between the groups either in their total ADI-R algorithm scores, or in their algorithm scores on individual domains. Social outcome ratings and ADI-R scores based on current functioning also failed to differentiate between the groups. Scores on tests of language comprehension and expression were also similar, but in both groups language abilities were well below chronological age level. The implications of these results with respect to the differences between Asperger syndrome and high-functioning autism are discussed. The poor performance on language tests also challenges the assumption that early language development in Asperger syndrome is essentially normal.

摘要

近年来,阿斯伯格综合征和高功能自闭症应被视为相同还是不同病症的问题一直是争论和争议的源头。在本研究中,将34名语言发育早期延迟的自闭症成年人与42名据报道在单词或短语使用方面无此类延迟的个体进行了比较。所有参与者年龄均至少为18岁,非言语智商为70或以上,且符合ADI-R关于发病年龄、沟通和社交障碍以及刻板行为的标准。语言延迟组的参与者被诊断为患有高功能自闭症。其余参与者被指定为患有阿斯伯格综合征。两组在年龄、非言语智商和性别方面进行了匹配。两组在ADI-R总算法得分或各个领域的算法得分上均未发现显著差异。基于当前功能的社交结果评分和ADI-R得分也未能区分两组。语言理解和表达测试的得分也相似,但两组的语言能力均远低于实际年龄水平。讨论了这些结果对于阿斯伯格综合征和高功能自闭症之间差异的意义。语言测试中的不佳表现也对阿斯伯格综合征早期语言发展基本正常这一假设提出了挑战。

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