Kitzmann Anna S, Weaver Amy L, Lohse Christine M, Buettner Helmut, Salomão Diva R
Mayo Medical School, Mayo Clinic, Rochester, MN, USA.
Am J Clin Pathol. 2003 Apr;119(4):594-601. doi: 10.1309/MLRM-QWAF-V6A1-15UA.
All surgical eye specimens examined in our pathology laboratory between January 1, 1990, and July 31, 2000 (N = 646), were classified by surgical procedure (enucleation, evisceration, or exenteration) and pathologic diagnosis. Among 523 enucleated globes (81.0%), 252 (48.2%) contained tumors, of which 208 were intraocular malignant melanomas. Nonneoplastic causes for enucleation included glaucoma (67/523 [12.8%]), phthisis bulbi (61/523 [11.7%]), and recent trauma (59/523 [11.3%]). Sixty-seven specimens (10.4%) had been eviscerated. Fifty-six specimens (8.7%) were obtained by exenteration performed to manage malignant tumors originating in or invading the orbit. Between 1990 and 2000, the percentage of procedures performed to remove neoplasms decreased from 65% to 38%, procedures performed to treat glaucoma increased from 4% to 29%, and those to treat phthisis bulbi increased from 8% to 13%. The numbers of procedures remained relatively constant for trauma and for infectious and inflammatory diseases.
1990年1月1日至2000年7月31日期间，在我们病理实验室检查的所有眼科手术标本（N = 646），均根据手术方式（眼球摘除术、眼内容剜出术或眶内容物剜出术）和病理诊断进行分类。在523例眼球摘除标本（81.0%）中，252例（48.2%）含有肿瘤，其中208例为眼内恶性黑色素瘤。眼球摘除的非肿瘤性原因包括青光眼（67/523 [12.8%]）、眼球痨（61/523 [11.7%]）和近期外伤（59/523 [11.3%]）。67例标本（10.4%）进行了眼内容剜出术。56例标本（8.7%）是通过眶内容物剜出术获得的，用于处理起源于眼眶或侵犯眼眶的恶性肿瘤。1990年至2000年期间，为切除肿瘤而进行的手术比例从65%降至38%，为治疗青光眼而进行的手术比例从4%增至29%，为治疗眼球痨而进行的手术比例从8%增至13%。因外伤以及感染和炎症性疾病而进行的手术数量保持相对稳定。
