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在一家参考中心接受治疗的患者中无眼球病因的患病率:一项回顾性研究。

Prevalence of anophthalmia etiological factors in patients treated in a reference center: A retrospective study.

作者信息

Penitente Paulo Augusto, Freitas da Silva Emily Vivianne, Pontes Manicoba Lorena Louise, Azevedo Romero Giovana Dornelas, Micheline Dos Santos Daniela, Goiato Marcelo Coelho

机构信息

Department of Dental Materials and Prosthodontics, Aracatuba Dental School, Sao Paulo State University (UNESP), Aracatuba, Sao Paulo, Brazil.

出版信息

Med J Armed Forces India. 2023 Sep-Oct;79(5):547-550. doi: 10.1016/j.mjafi.2021.06.025. Epub 2021 Sep 1.

Abstract

BACKGROUND

Ocular prosthesis rehabilitation has an important social, psychological, esthetic, and functional role. Congenital factors, trauma, and tumors, among others, can cause anophthalmia, and it is essential to identify the etiology to guide its prevention and treatment.

METHODS

The aim of this study was to retrospectively investigate the records of patients treated from 2013 to 2020 by the Oral and Maxillofacial Prosthesis Group, aiming to identify the prevalence of patients with anophthalmia and the etiology of their anophthalmia. After approval by the Human Research Ethics Committee, two calibrated researchers evaluated 520 records, identifying those from patients with anophthalmia. The inclusion criteria were records with complete and legible information from patients with anophthalmia and a description of their etiology. Descriptive statistics were performed, and etiological factors were categorized into trauma, congenital cause, end-stage eye disease, and tumor. Spearman's correlation was performed to verify the relation between gender and anophthalmia etiology, with a 5% significance level. Seventy-two records were included in the study.

RESULTS

It was observed that 33.4% of patients were women and 66.6% were men. The etiologies were physical trauma (52.4%), tumor (21.8%), end-stage eye disease (16.6%), and congenital cause (9.2%), and there was no correlation between gender and these etiologies ( .301).

CONCLUSION

Most of the cases identified were of traumatic origin, which allows the establishment of preventive and educational measures to avoid new cases of anophthalmia.

摘要

背景

眼部假体康复具有重要的社会、心理、美学和功能作用。先天性因素、创伤和肿瘤等可导致无眼球,明确病因对于指导其预防和治疗至关重要。

方法

本研究旨在回顾性调查口腔颌面修复组2013年至2020年治疗的患者记录,以确定无眼球患者的患病率及其无眼球的病因。经人类研究伦理委员会批准后,两名经过校准的研究人员评估了520份记录,确定了无眼球患者的记录。纳入标准为有无眼球患者的完整且清晰可读的信息以及对其病因的描述。进行了描述性统计,并将病因分为创伤、先天性病因、终末期眼病和肿瘤。采用Spearman相关性分析来验证性别与无眼球病因之间的关系,显著性水平为5%。本研究纳入了72份记录。

结果

观察到33.4%的患者为女性,66.6%为男性。病因包括身体创伤(52.4%)、肿瘤(21.8%)、终末期眼病(16.6%)和先天性病因(9.2%),性别与这些病因之间无相关性(.301)。

结论

大多数确诊病例为创伤性起源,这有助于制定预防和教育措施以避免新的无眼球病例。

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