Duncan G W, Gruber J O, Dewey C F, Myers G S, Lees R S
N Engl J Med. 1975 Nov 27;293(22):1124-8. doi: 10.1056/NEJM197511272932205.
Quantitative spectral (frequency) analyses were performed on 60 carotid bruits in 48 patients with suspected carotid stenosis. The technic was totally noninvasive. Bruits were recorded at the skin surface, analyzed by a minicomputer, and the degree of arterial stenosis estimated using a recently derived theory of sound production by turbulent blood flow. This method has been named phonoangiography. Fifty of the 60 bruits (83 per cent) had spectrums characteristic of turbulent blood flow, and a residual lumen diameter could be calculated. Results from the noninvasvie technic compared well with data obtained from radiographic carotid arteriograms in the 50 bruits with internal carotid artery stenosis. The residual lumen diameter estimated from phonoangiography differed from the radiographic value by less than 1 mm in 83 per cent and less than 1.5 mm in 92 per cent of the studies. Phonoangiography appears to be a useful method for assessment of carotid artery stenosis.
对48例疑似颈动脉狭窄患者的60处颈动脉杂音进行了定量频谱（频率）分析。该技术完全无创。在皮肤表面记录杂音，由小型计算机进行分析，并使用最近推导的湍流血液产生声音的理论估计动脉狭窄程度。这种方法被称为血管音造影。60处杂音中有50处（83%）具有湍流血液的频谱特征，并且可以计算残余管腔直径。在50处有颈内动脉狭窄的杂音中，无创技术的结果与从颈动脉造影获得的数据比较良好。在83%的研究中，血管音造影估计的残余管腔直径与造影值相差不到1毫米，在92%的研究中相差不到1.5毫米。血管音造影似乎是评估颈动脉狭窄的一种有用方法。
