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接受腹膜透析的儿童的出口处感染:两种腹膜导管的比较

Exit-site infection in children on peritoneal dialysis: comparison of two types of peritoneal catheters.

作者信息

Warchol Stanislaw, Ziolkowska Helena, Roszkowska-Blaim Maria

机构信息

Department of Cardiac Surgery and General Pediatric Surgery, Medical University of Warsaw, Warsaw, Poland.

出版信息

Perit Dial Int. 2003 Mar-Apr;23(2):169-73.

PMID:12713085
Abstract

OBJECTIVE

To review our experience with two types of peritoneal catheters, the standard Tenckhoff catheter and the swan-neck presternal catheter (SNPC).

DESIGN

A retrospective study was undertaken to compare exit-site infection (ESI) rates using two types of peritoneal catheters in children.

SETTING

Medical University of Warsaw, Warsaw, Poland.

PATIENTS

During the past 10 years, 60 peritoneal catheters were implanted in 50 children with end-stage renal failure: 46 straight, double-cuffed Tenckhoff in 37 children (mean age 11.8 +/- 4.2 years, range 3.1 - 18.5 years), and 14 presternal in 13 children (mean age 10.6 +/- 5 years, range 0.3-17.7 years). The SNPCs were used in special clinical situations such as recurrent ESI with previous abdominal peritoneal catheters, obesity, presence of ureterocutaneostomies, use of diapers, and young age. For the statistical analysis, only the first catheter placed in each child was chosen: 34 standard Tenckhoff catheters and 9 SNPCs.

INTERVENTION

In all children, peritoneal catheters were implanted surgically under general anesthesia by one surgeon; uniform operative technique and perioperative management was used.

RESULTS

The mean observation time for 46 standard Tenckhoff catheters was 23.8 +/- 21.1 months, and for 14 SNPCs 25.1 +/- 27.0 months. The ESI rate was 1/17.4 patient-months (0.69 episodes/year) for Tenckhoff catheters and 1/70.2 patient-months (0.17 episodes/year) for SNPCs. The observed differences in ESI rates between the groups reported did not achieve statistical significance.

CONCLUSIONS

The risk of ESI may be lower with presternal catheters. Confirmation of these findings requires further prospective clinical investigation in large numbers of patients.

摘要

目的

回顾我们使用两种类型腹膜导管(标准Tenckhoff导管和天鹅颈胸骨前导管[SNPC])的经验。

设计

进行一项回顾性研究,比较儿童使用两种类型腹膜导管的出口部位感染(ESI)率。

地点

波兰华沙医科大学。

患者

在过去10年中,为50例终末期肾衰竭儿童植入了60根腹膜导管:37例儿童植入了46根直的、双套囊Tenckhoff导管(平均年龄11.8±4.2岁,范围3.1 - 18.5岁),13例儿童植入了14根胸骨前导管(平均年龄10.6±5岁,范围0.3 - 17.7岁)。SNPC用于特殊临床情况,如既往腹部腹膜导管反复发生ESI、肥胖、存在输尿管皮肤造口术、使用尿布以及年龄较小。为进行统计分析,仅选择每个儿童植入的第一根导管:34根标准Tenckhoff导管和9根SNPC。

干预

所有儿童均在全身麻醉下由一名外科医生通过手术植入腹膜导管;采用统一的手术技术和围手术期管理。

结果

46根标准Tenckhoff导管的平均观察时间为23.8±21.1个月,14根SNPC的平均观察时间为25.1±27.0个月。Tenckhoff导管的ESI率为1/17.4患者-月(0.69次/年),SNPC的ESI率为1/70.2患者-月(0.17次/年)。所报告的两组之间ESI率的观察差异未达到统计学意义。

结论

胸骨前导管的ESI风险可能较低。这些发现需要在大量患者中进行进一步的前瞻性临床研究加以证实。

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