Quistorff Bjørn, Grunnet Niels
Københavns Universitet, Panum Instituttet, Stofskiftecentret, Institut for Medicinsk Biokemi og Genetik.
Ugeskr Laeger. 2003 Apr 7;165(15):1551-2.
The basic biochemistry of de novo lipogenesis and the current understanding of fat formation from carbohydrates in humans are reviewed. The suggestion is made that ingestion of carbohydrates in excess of the caloric needs necessarily results in de novo lipogenesis since the glycogen stores are already full. Under these circumstances a formation per day of 15-20 g palmitate from carbohydrates has been reported in the liver and a similar amount in the peripheral tissues.
本文综述了从头脂肪生成的基本生物化学以及目前对人体中碳水化合物形成脂肪的理解。有人提出，摄入超过热量需求的碳水化合物必然会导致从头脂肪生成，因为糖原储备已经饱和。在这种情况下，据报道肝脏每天可从碳水化合物中生成15 - 20克棕榈酸酯，外周组织中生成的量与之相似。
