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用于评估过氧乙酸基消毒剂的替代AOAC杀孢子试验载体(AOAC官方方法966.04的修订版)

Alternative AOAC sporicidal test carrier for evaluating peracetic acid-based sterilants (modification of AOAC official method 966.04).

作者信息

McDonnell Gerald

机构信息

STERIS Corp., 5960 Heisley Rd, Mentor, OH 44060-1834, USA.

出版信息

J AOAC Int. 2003 Mar-Apr;86(2):407-11.

PMID:12723925
Abstract

Dacron suture loops were demonstrated to be inert, consistent carriers in the presence of peracetic acid-based sterilants, whereas black silk sutures had a variable preparation process and interacted with peracetic acid. In addition, Dacron suture loops provided comparable spore loading to black silk suture loops and an HCI resistance of > or = 2 min. These results indicate that black silk suture loops are not appropriate carriers for assessing peracetic acid-based sterilants, and Dacron loops are an acceptable alternative. This finding is consistent with the Office of Science and Technology Laboratory (Center for Devices and Radiological Health) study which determined that "polyester suture material is a viable alternative to silk for the AOAC sporicidal test for liquid disinfectants."

摘要

已证明涤纶缝合线环在过氧乙酸基消毒剂存在时是惰性的、稳定的载体,而黑色丝线缝合线的制备过程存在差异且会与过氧乙酸发生相互作用。此外,涤纶缝合线环与黑色丝线缝合线环的孢子负载量相当,耐盐酸时间≥2分钟。这些结果表明,黑色丝线缝合线环不是评估过氧乙酸基消毒剂的合适载体,而涤纶线环是可接受的替代物。这一发现与科学技术实验室(设备与放射卫生中心)的研究结果一致,该研究确定“聚酯缝合材料是用于液体消毒剂AOAC杀孢子试验的丝绸的可行替代品”。

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引用本文的文献

1
Evaluation of AISI Type 304 stainless steel as a suitable surface material for evaluating the efficacy of peracetic acid-based disinfectants against Clostridium difficile spores.评估AISI 304型不锈钢作为一种合适的表面材料,用于评估过氧乙酸基消毒剂对艰难梭菌芽孢的消毒效果。
PLoS One. 2017 Oct 24;12(10):e0187074. doi: 10.1371/journal.pone.0187074. eCollection 2017.
2
The differential effects of heat-shocking on the viability of spores from Bacillus anthracis, Bacillus subtilis, and Clostridium sporogenes after treatment with peracetic acid- and glutaraldehyde-based disinfectants.过氧乙酸和戊二醛基消毒剂处理后,热休克对炭疽芽孢杆菌、枯草芽孢杆菌和生孢梭菌孢子活力的差异影响。
Microbiologyopen. 2015 Oct;4(5):764-73. doi: 10.1002/mbo3.277. Epub 2015 Jul 17.