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[维生素E琥珀酸酯对人胃癌细胞生长的抑制作用]

[Inhibition of human gastric carcinoma cell growth by vitamin E succinate].

作者信息

Liu B, Wu K, Zhao D

机构信息

Public Health School of Harbin Medical University, Harbin 150001, China.

出版信息

Wei Sheng Yan Jiu. 2000 May 30;29(3):172-4.

PMID:12725068
Abstract

The effects of vitamin E succinate (VES) on the growth of human gastric carcinoma cell (SGC-7901) were examined and compared with the effects of alpha-tocopherol by MTT assay. It was found that VES(5, 10 and 20 micrograms/ml) inhibited cell growth significantly, but alpha-tocopherol did not show any inhibition effects. The results showed that the anticancer effect of VES and the anticancer mechanism of VES is different from alpha-tocopherol.

摘要

通过MTT法检测了维生素E琥珀酸酯（VES）对人胃癌细胞（SGC-7901）生长的影响，并与α-生育酚的作用进行了比较。发现VES（5、10和20微克/毫升）能显著抑制细胞生长，但α-生育酚未显示出任何抑制作用。结果表明，VES的抗癌作用及其抗癌机制与α-生育酚不同。

相似文献

1
[Inhibition of human gastric carcinoma cell growth by vitamin E succinate].[维生素E琥珀酸酯对人胃癌细胞生长的抑制作用]
Wei Sheng Yan Jiu. 2000 May 30;29(3):172-4.
2
[Effect of different vitamin E homologous analogues on human hepatoma cell HepG2 proliferation in vitro].
Wei Sheng Yan Jiu. 2003 Jan;32(1):40-3.
3
[Study on vitamin E succinate inducing apoptosis of human gastric carcinoma cell].
Wei Sheng Yan Jiu. 2000 Jul;29(4):234-6.
4
[Roles of ERK1/2 MAPK in vitamin E succinate-induced apoptosis in human gastric cancer SGC-7901 cells].[细胞外信号调节激酶1/2丝裂原活化蛋白激酶在维生素E琥珀酸酯诱导人胃癌SGC - 7901细胞凋亡中的作用]
Wei Sheng Yan Jiu. 2003 Nov;32(6):573-5.
5
RRR-alpha-tocopheryl succinate inhibits human gastric cancer SGC-7901 cell growth by inducing apoptosis and DNA synthesis arrest.RRR-α-生育酚琥珀酸酯通过诱导细胞凋亡和DNA合成阻滞来抑制人胃癌SGC-7901细胞的生长。
World J Gastroenterol. 2002 Feb;8(1):26-30. doi: 10.3748/wjg.v8.i1.26.
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[Effect of apoptosis induced by different vitamin E homologous analogues in human hepatoma cells(HepG2)].[不同维生素E同源类似物诱导人肝癌细胞（HepG2）凋亡的作用]
Wei Sheng Yan Jiu. 2003 Jul;32(4):343-5.
7
[Effect of apoptosis induced by different vitamin E homologous analogues in human hepatoma cells (HepG2)].[不同维生素E同源类似物诱导人肝癌细胞（HepG2）凋亡的作用]
Wei Sheng Yan Jiu. 2003 Mar;32(2):131-3.
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[The expression and activity of caspase-8 in the process of vitamin E succinate-induced apoptosis in human gastric carcinoma SGC-7901 cells].[维生素E琥珀酸酯诱导人胃癌SGC-7901细胞凋亡过程中caspase-8的表达及活性]
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Differential response of human ovarian cancer cells to induction of apoptosis by vitamin E Succinate and vitamin E analogue, alpha-TEA.人卵巢癌细胞对维生素E琥珀酸酯和维生素E类似物α-TEA诱导凋亡的差异反应。
Cancer Res. 2004 Jun 15;64(12):4263-9. doi: 10.1158/0008-5472.CAN-03-2327.
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Peptide YY augments gross inhibition by vitamin E succinate of human pancreatic cancer cell growth.肽YY增强了维生素E琥珀酸酯对人胰腺癌细胞生长的总体抑制作用。
J Surg Res. 2000 Jan;88(1):23-5. doi: 10.1006/jsre.1999.5775.

引用本文的文献

1
c-Jun N-terminal kinase is required for vitamin E succinate-induced apoptosis in human gastric cancer cells.人胃癌细胞中维生素E琥珀酸酯诱导的细胞凋亡需要c-Jun氨基末端激酶。
World J Gastroenterol. 2004 Apr 15;10(8):1110-4. doi: 10.3748/wjg.v10.i8.1110.
2
Roles of Fas signaling pathway in vitamin E succinate-induced apoptosis in human gastric cancer SGC-7901 cells.Fas信号通路在维生素E琥珀酸酯诱导人胃癌SGC-7901细胞凋亡中的作用
World J Gastroenterol. 2002 Dec;8(6):982-6. doi: 10.3748/wjg.v8.i6.982.
3
The effects of vitamin E succinate on the expression of c-jun gene and protein in human gastric cancer SGC-7901 cells.
维生素E琥珀酸酯对人胃癌SGC-7901细胞中c-jun基因及蛋白表达的影响
World J Gastroenterol. 2002 Oct;8(5):782-6. doi: 10.3748/wjg.v8.i5.782.
4
RRR-alpha-tocopheryl succinate inhibits human gastric cancer SGC-7901 cell growth by inducing apoptosis and DNA synthesis arrest.RRR-α-生育酚琥珀酸酯通过诱导细胞凋亡和DNA合成阻滞来抑制人胃癌SGC-7901细胞的生长。
World J Gastroenterol. 2002 Feb;8(1):26-30. doi: 10.3748/wjg.v8.i1.26.