Saigal Saroj, Pinelli Janet, Hoult Lorraine, Kim M Marie, Boyle Michael
Department of Pediatrics, McMaster University, Hamilton, Ontario, Canada.
Pediatrics. 2003 May;111(5 Pt 1):969-75. doi: 10.1542/peds.111.5.969.
We have previously shown that infants who were extremely low birth weight (ELBW) are particularly vulnerable to problems related to inattention and hyperactivity at school age. It is not known whether these problems persist to adolescence.
To explore and compare the levels of psychopathology in a regional cohort of ELBW infants and sociodemographically matched term controls as reported by teens and their parents.
DESIGN/METHODS: Cross-sectional cohort study/geographically defined region.
TEENS: ELBW 141/169 (83%) and control 122/145 (84%), aged 12 to 16 years. PARENTS: ELBW 143/169 (85%) and control 123/145 (85%). Both cohorts and their parents completed the Ontario Child Health Study-Revised questionnaire with 6 behavioral subsca1es: conduct disorder, oppositional defiant disorder, attention-deficit/hyperactivity disorder (ADHD), overanxious, separation anxiety, and depression.
By teen self-report, there were no significant differences between ELBW and control teens on any of the 6 subscale scores. However, parents of ELBW teens reported significantly higher scores than parents of control for depression and ADHD based on 2-way analysis of variance (group x gender). Comparison within teen/parent dyads showed that both cohorts of teens reported significantly higher scores than their parents. Multivariable analyses on behavioral subscale scores demonstrated a number of variables that were significant predictors by parent report: group (ELBW vs control), gender, family function, developmental quotient, maternal mood, and socioeconomic status; no predictors were significant by teen report. There were no statistically significant interaction effects for any of the models. These models explained a greater percent of the variance in behavioral scores for parents than for teens (12.5%-22.0% vs 3.4%-8.2%). Results were similar when teens with neurosensory impairment were excluded.
This study is unique in the inclusion of both parent and teen self-report of behaviors. Significant differences were apparent only by parent report for ADHD and depression among ELBW teens. Significant predictors of behavioral scores for parents include group, gender, family function, developmental quotient, maternal mood, and socioeconomic status.
我们之前已经表明，极低出生体重（ELBW）的婴儿在学龄期特别容易出现与注意力不集中和多动相关的问题。目前尚不清楚这些问题是否会持续到青春期。
探讨并比较青少年及其父母报告的ELBW婴儿区域队列和社会人口统计学匹配的足月儿对照的心理病理学水平。
设计/方法：横断面队列研究/地理界定区域。
青少年：ELBW组141/169（83%），对照组122/145（84%），年龄12至16岁。父母：ELBW组143/169（85%），对照组123/145（85%）。两个队列及其父母均完成了安大略儿童健康研究修订版问卷，该问卷有6个行为子量表：品行障碍、对立违抗障碍、注意力缺陷/多动障碍（ADHD）、过度焦虑、分离焦虑和抑郁。
根据青少年自我报告，ELBW青少年和对照青少年在6个子量表得分中的任何一项上均无显著差异。然而，基于双向方差分析（组×性别），ELBW青少年的父母报告的抑郁和ADHD得分显著高于对照组的父母。青少年/父母二元组内的比较显示，两个队列的青少年报告的得分均显著高于其父母。对行为子量表得分的多变量分析表明，父母报告中有多个变量是显著的预测因素：组（ELBW与对照）、性别、家庭功能、发育商、母亲情绪和社会经济地位；青少年报告中没有显著的预测因素。任何模型均无统计学上显著的交互作用。这些模型解释的父母行为得分方差百分比高于青少年（12.5%-22.0%对3.4%-8.2%）。排除有神经感觉障碍的青少年后结果相似。
本研究的独特之处在于纳入了父母和青少年对行为的自我报告。仅父母报告显示ELBW青少年在ADHD和抑郁方面存在显著差异。父母行为得分的显著预测因素包括组、性别、家庭功能、发育商、母亲情绪和社会经济地位。
