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治疗小儿失眠症的药物使用情况:一项针对社区儿科医生的调查结果

Medication use in the treatment of pediatric insomnia: results of a survey of community-based pediatricians.

作者信息

Owens Judith A, Rosen Carol L, Mindell Jodi A

机构信息

Department of Pediatrics and Division of Ambulatory Pediatrics, Brown Medical School, Providence, Rhode Island, USA.

出版信息

Pediatrics. 2003 May;111(5 Pt 1):e628-35. doi: 10.1542/peds.111.5.e628.

Abstract

OBJECTIVES

To examine clinical practice patterns, beliefs, and attitudes regarding the use of both nonprescription and prescription medications by community-based pediatricians for children with significant difficulties in initiating and/or maintaining sleep.

METHODS

A survey was mailed to 3424 American Academy of Pediatrics members in 6 US cities.

RESULTS

The final sample (n = 671) consisted of practitioners who identified themselves as primary care pediatricians. Three percent +/- 7% of visits in the respondents' practices were for pediatric insomnia, although there was a wide range in the numbers of children identified during a typical 6-month practice period. More than 75% of practitioners had recommended nonprescription medications, and >50% had prescribed a sleep medication. Specific clinical circumstances in which medications were most commonly used were acute pain and travel, followed by children with special needs (mental retardation, autism, and attention-deficit/hyperactivity disorder). Antihistamines were the most commonly reported nonprescription medications for sleep. Melatonin or herbal remedies had been recommended by approximately 15% of the respondents. alpha-agonists were the most frequently prescribed sleep medications (31%). The likelihood of prescribing medication for sleep was 2- to 4-fold greater in respondents who treated children with attention-deficit/hyperactivity disorder for daytime behavioral problems or nocturnal sleep problems, respectively. Practitioners expressed a range of concerns about sleep medication appropriateness, safety, tolerance, and side effects in children.

CONCLUSIONS

The practice of prescribing or recommending sedatives and hypnotics for pediatric insomnia is common among community-based pediatricians, especially among special needs patients. An empirically based approach to the use of these medications is needed.

摘要

目的

探讨社区儿科医生针对入睡和/或维持睡眠存在显著困难的儿童使用非处方药和处方药的临床实践模式、信念及态度。

方法

向美国6个城市的3424名美国儿科学会成员邮寄了一份调查问卷。

结果

最终样本(n = 671)由自认为是初级保健儿科医生的从业者组成。在受访者的诊疗实践中,3%±7%的就诊是关于儿童失眠的,尽管在典型的6个月诊疗期内确诊的儿童数量差异很大。超过75%的从业者推荐过非处方药,超过50%的从业者曾开过助眠药物。药物最常使用的具体临床情况是急性疼痛和旅行,其次是有特殊需求的儿童(智力迟钝、自闭症和注意力缺陷多动障碍)。抗组胺药是最常被报告用于助眠的非处方药。约15%的受访者推荐过褪黑素或草药疗法。α-激动剂是最常被开具的助眠药物(31%)。分别因白天行为问题或夜间睡眠问题而治疗患有注意力缺陷多动障碍儿童的受访者,开具助眠药物的可能性要高出2至4倍。从业者对儿童助眠药物的适用性、安全性、耐受性和副作用表达了一系列担忧。

结论

在社区儿科医生中,尤其是在有特殊需求的患者中,为儿童失眠开具或推荐镇静催眠药的做法很常见。需要一种基于实证的方法来使用这些药物。

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