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两年期间商用抗球蛋白血清的评估。第一部分。抗β1A、抗α2D和抗β1E水平。

Evaluation of commercial antiglobulin sera over a two-year period. Part I. Anti-beta 1A, anti-alpha 2D, and anti-beta 1E levels.

作者信息

Issitt P D, Issitt C H, Wilkinson S L

机构信息

Paul I. Hoxworth Blood Center of the University of Cincinnati, Cincinnati, Ohio, 45229, USA.

出版信息

Transfusion. 1974 Mar-Apr;14(2):93-102. doi: 10.1111/j.1537-2995.1974.tb04498.x.

DOI:10.1111/j.1537-2995.1974.tb04498.x
PMID:12731580
Abstract

Antiglobulin sera from nine different manufacturers have been tested, over a two-year period, for their ability to detect the complement components beta 1A, alpha 2D, and beta 1E. The results demontrate considerable variation in the abilities of sera from different manufacturers to detect these components and indicate that not all sera on the market are suitable reagents for diagnostic use and compatibility tests. The results also show that there is considerable variation between different lots of serum from some of the manufacturers. In general, the anti-complement levels of these reagents have increased during the two-year period of study but not all companies produce suitable reagents for routine use.

摘要

在两年时间里,对来自九个不同制造商的抗球蛋白血清检测了它们检测补体成分β1A、α2D和β1E的能力。结果表明,不同制造商的血清在检测这些成分的能力上存在相当大的差异,这表明市场上并非所有血清都是适用于诊断用途和相容性测试的试剂。结果还显示,一些制造商不同批次的血清之间也存在相当大的差异。总体而言,在为期两年的研究期间,这些试剂的抗补体水平有所提高,但并非所有公司都生产适用于常规使用的试剂。

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引用本文的文献

1
Quantitation of C3 subcomponents on red cells coated with complement in vitro.体外补体包被红细胞上C3亚成分的定量分析。
J Clin Pathol. 1980 Oct;33(10):977-83. doi: 10.1136/jcp.33.10.977.