Uemura Tadahiro, Kurita Akira, Nishimura Rieko, Ishizaki Masahiro, Takashima Shigemitsu
Department of Surgery, National Shikoku Cancer Center, 13 Horinouchi, Matsuyama 790-0007, Japan.
Surg Today. 2003;33(5):395-8. doi: 10.1007/s005950300090.
The pancreas is an uncommon site for metastasis from renal cell carcinoma. We report the case of a 70-year-old man in whom a solitary pancreatic metastasis from renal cell carcinoma, found 17 years after nephrectomy, was successfully resected, combined with gastrectomy for early gastric cancer. We also discuss the relevant literature, including all the reports of pancreatic metastasis from renal cell carcinoma found in Medline. More than half the cases, like ours, were asymptomatic. A good prognosis can be expected once the pancreatic metastatic lesions are surgically excised, especially if it is a solitary metastasis. Therefore, surgical resection of pancreatic metastases is recommended to achieve the best chance of long-term survival. Special attention must be paid to the possibility of recurrence, even more than 10 years after nephrectomy for renal cell carcinoma, and imaging modalities should be part of the routine follow-up to detect metastases at an early stage.
胰腺是肾细胞癌转移的罕见部位。我们报告了一例70岁男性患者，其在肾切除术后17年发现了孤立性肾细胞癌胰腺转移灶，并成功进行了切除，同时因早期胃癌行胃切除术。我们还讨论了相关文献，包括Medline中发现的所有肾细胞癌胰腺转移的报告。超过半数的病例，如我们的病例，是无症状的。一旦手术切除胰腺转移灶，尤其是孤立性转移灶，有望获得良好的预后。因此，建议手术切除胰腺转移灶以获得最佳的长期生存机会。必须特别注意复发的可能性，即使在肾细胞癌肾切除术后10多年，影像学检查应作为常规随访的一部分，以便早期发现转移灶。
