Fine D H, Rounbehler D P, Belcher N M
Science. 1976 Jun 25;192(4246).
By use of a new, highly selective detection technique for N-nitroso compounds, which is sensitive to picogram quantities and which is based on the catalytic cleavage of the N-NO bond and the subsequent detection of the nitrosyl radical, dimethylnitrosamine has been found in concentrations of 0.02 to 0.96 part per billion in three out of five air samples from Baltimore, Maryland, and 0.014 to 0.051 part per billion in five out of six air samples from Belle, West Virginia. The sensitivity of the analytical procedures used was 1 part in 10(12). The presence of dimethylnitrosamine has been confirmed by using the new detector in conjunction with both a gas-liquid chromatograph and a high-performance liquid chromatograph. In addition, between one and three as yet unidentified N-nitroso compounds were detected in both cities. N-Nitroso compounds were not found in air samples from Philadelphia, Pennsylvania; Wilmington, Delaware; and Waltham, Massachusetts.
通过使用一种新型的、对N-亚硝基化合物具有高选择性的检测技术，该技术对皮克级量敏感，基于N-NO键的催化裂解及随后对亚硝酰基自由基的检测，在来自马里兰州巴尔的摩的五份空气样本中的三份中发现二甲基亚硝胺浓度为十亿分之0.02至0.96，在来自西弗吉尼亚州贝尔的六份空气样本中的五份中发现其浓度为十亿分之0.014至0.051。所采用分析程序的灵敏度为10的12次方分之一。通过将新型检测器与气相色谱仪和高效液相色谱仪联用，已证实二甲基亚硝胺的存在。此外，在这两个城市均检测到一至三种尚未鉴定的N-亚硝基化合物。在来自宾夕法尼亚州费城、特拉华州威尔明顿和马萨诸塞州沃尔瑟姆的空气样本中未发现N-亚硝基化合物。
