Rappe C, Rydström T
IARC Sci Publ. 1980(31):565-74.
N-Nitrosodiphenylamine is used as an additive in the rubber industry. This N-nitrosamine has not been associated with carcinogenic effects in laboratory animals. However, it can serve as a powerful transnitrosation agent, reacting with amines present in the rubber mixture to form other N-nitrosamines; e.g., N-nitrosodibutylamine from di-n-butylamine and N-nitrosodimethylamine from tetramethylthiuram disulfide. Di-n-butylamine and tetramethylthiuram disulfide are both used as additives in the rubber industry.
N-亚硝基二苯胺在橡胶工业中用作添加剂。这种N-亚硝胺在实验动物中未发现有致癌作用。然而，它可作为一种强效的亚硝化剂，与橡胶混合物中的胺反应形成其他N-亚硝胺；例如，由二正丁胺形成N-亚硝基二丁胺，由二硫化四甲基秋兰姆形成N-亚硝基二甲胺。二正丁胺和二硫化四甲基秋兰姆在橡胶工业中均用作添加剂。
