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Bone cells in culture: morphologic transformation by hormones.

作者信息

Miller S S, Wolf A M, Arnaud C D

出版信息

Science. 1976 Jun 25;192(4246):1340-3. doi: 10.1126/science.1273593.

DOI:10.1126/science.1273593
PMID:1273593
Abstract

Hormones and purine nucleosides and nucleotides induced cultured bone cells to transform transiently from a spherical to a stellate shape. Cytochalasin B also induced the transformation. The change was blocked by colchicine and vinblastine, but not by lumicolchicine or cycloheximide. This morphologic transformation may provide a dynamic model of hormone action and bone cell modulation in vitro.

摘要

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