Cobellis L, Pecori E, Stradella L, De Lucia E, Messalli E M, Cobellis G
Department of Obstetrics and Gynecology, Second University of Naples, Naples, Italy.
Gynecol Endocrinol. 2003 Apr;17(2):95-9.
The ovarian hyperstimulation syndrome (OHSS) is an iatrogenic, unpredictable and potentially life-threatening complication in patients submitted to pharmacological ovarian stimulation. Information on risk factors, etiopathogenetic mechanisms, prevention strategies and therapeutic management is continuously updated. The present study retrospectively analyzed 123 women affected by different grades of OHSS as a result of pharmacological ovulation induction. Hospital admission was suggested in 14 patients with severe OHSS, whereas patients with moderate or mild OHSS were followed in the out-patient section of our department. The results confirmed the efficacy of the therapeutic scheme adopted. The syndrome is localized to the ovaries at the time that the condition is triggered; when organs different from the ovaries become involved, OHSS assumes systemic aspects. The different clinical signs are the basis of a proposal of a local and systemic classification.
卵巢过度刺激综合征（OHSS）是接受药物性卵巢刺激的患者中一种医源性、不可预测且可能危及生命的并发症。关于危险因素、病因发病机制、预防策略和治疗管理的信息不断更新。本研究回顾性分析了123例因药物性促排卵而发生不同程度OHSS的女性。14例重度OHSS患者建议住院治疗，而中度或轻度OHSS患者在本部门门诊进行随访。结果证实了所采用治疗方案的有效性。该综合征在发病时局限于卵巢；当非卵巢器官受累时，OHSS呈现全身性表现。不同的临床体征是局部和全身分类建议的基础。
