Grønlund L A, Bogstad J W
Gynaekologisk-obstetrisk afdeling, Amtssygehuset i Gentofte.
Ugeskr Laeger. 1996 Dec 9;158(50):7205-9.
Ovarian hyperstimulation syndrome (OHSS) is an iatrogenic, potentially life-threatening condition associated with ovulation induction. With increasing numbers of women receiving various ovarian stimulation protocols as part of different infertility treatments, the number of cases is likely to increase. The syndrome has a wide spectrum of clinical and laboratory findings, and is classified into mild, moderate and severe OHSS. The pathophysiology of this syndrome is unclear, and medical management has traditionally been conservative and supportive consisting of bedrest, volume expanders and replacement of fluid. When ascites is present, paracentesis under ultrasound guidance has been found to improve the condition of the patient by reducing the hydrostatic pressure. Prevention is very important, but at present it is doubtful if OHSS can be completely avoided due to the existence of a relatively small margin of safety between successful induction of ovulation and the development of OHSS.
卵巢过度刺激综合征（OHSS）是一种与排卵诱导相关的医源性、潜在危及生命的病症。随着越来越多的女性接受各种卵巢刺激方案作为不同不孕治疗的一部分，病例数量可能会增加。该综合征有广泛的临床和实验室表现，分为轻度、中度和重度OHSS。这种综合征的病理生理学尚不清楚，传统上医疗管理一直是保守和支持性的，包括卧床休息、扩容剂和液体补充。当出现腹水时，已发现超声引导下的腹腔穿刺可通过降低静水压力来改善患者状况。预防非常重要，但目前由于在成功诱导排卵和OHSS发生之间存在相对较小的安全 margin，是否能完全避免OHSS值得怀疑。 （注：原文中“margin”可能有误，推测可能是“margin of safety”即安全边际之意，这里按原文翻译存疑）
