Jókay I, Karczag E
Z Immunitatsforsch Exp Klin Immunol. 1975 May;148(5):414-24.
Injection of endotoxin into the peritoneal cavity of mice causes an early emigration of PMN-leucocytes and therafter a decrease in macrophage count. The number of lymphocytes shows only a transient increase. One and 2 injections of endotoxin rise the fibrinogen and protein level of the peritoneal fluid. A simple test for measuring the change in permeability (and lymph circulation) was described ("congo red elimination's test"). Changes in permeability occur after a latent period of 2 hours following endotoxin administration, culminate during the 1st day and last about 3-4 days. The possible mechanisms of the above phenomena are discussed.
向小鼠腹腔注射内毒素会导致中性粒细胞早期迁移，随后巨噬细胞数量减少。淋巴细胞数量仅出现短暂增加。注射一次和两次内毒素会使腹腔液中纤维蛋白原和蛋白质水平升高。描述了一种测量通透性变化（以及淋巴循环）的简单试验（“刚果红清除试验”）。内毒素给药后2小时的潜伏期后会出现通透性变化，在第一天达到高峰，并持续约3 - 4天。讨论了上述现象的可能机制。
