Hladny J, Metz H
Zentralbl Bakteriol Orig A. 1976 Mar;234(2):177h.
The distribution of serogroups among 156 strains of beta-hemolyzing streptococci from clinical material was as follows: A - 64.1%, B - 3.2%, C - 11.5%, D - 0.6%, F- 6.4%, G - 14.1% (Table 1). Serogroup A was found in pus specimens in 84%, in throat swabs in 67%, and in sputum specimens (x2 greater than 6.64) in only 23% of strains; among clinical diagnoses (Table 2), distribution of this group was as follows: scarlet fever 100%, infected wounds 83%, and otorhinolaryngological diseases less than 70% of strains. From 54% of specimens received, other organisms were isolated in addition to beta-hemolyzing streptococci, In Table 3, the distribution of serogroups (x2 greater than 1) in cases of single and mixed infections is shown for the most frequent types of material received. Combinations of the individual serogroups with concomitant bacteria, above all Staphylococcus aureus, a number of enterobacteria, and Haemophilus influenzae can be seen from Table 4. Staph. aureus was found preferentially in combination with group A streptococci (x2 greater then 6.64). The proportion of mixed infections among specimens of the most important types of material was varying (Table 5): 82% of sputum specimens, 46%of throat swabs, and 39% of pus specimens. As concomitant organisms, especially Haem. influenzae, Staph. aureus (in throat swabs and pus specimens), and enterobacteria were found. With scarlet fever, Staph. aureus was present in as much as 60% of all cases. Ampicillin-resistant strains were isolated among the various concomitant organisms from 22% of all materials and 45% of all sputum specimens.
从临床材料中分离出的156株β溶血性链球菌的血清群分布如下:A群 - 64.1%,B群 - 3.2%,C群 - 11.5%,D群 - 0.6%,F群 - 6.4%,G群 - 14.1%(表1)。A群在84%的脓液标本、67%的咽拭子标本中被发现,而在痰标本中(χ²>6.64)仅23%的菌株中被发现;在临床诊断中(表2),该群的分布如下:猩红热100%,感染伤口83%,耳鼻喉科疾病中该群菌株占比不到70%。在54%的送检标本中,除了β溶血性链球菌外还分离出了其他微生物。表3显示了所接收的最常见类型材料中单一感染和混合感染病例的血清群分布(χ²>1)。从表4可以看出各个血清群与伴随细菌的组合情况,其中最主要的是金黄色葡萄球菌、一些肠道杆菌和流感嗜血杆菌。金黄色葡萄球菌优先与A群链球菌组合(χ²>6.64)。最重要类型材料的标本中混合感染的比例各不相同(表5):痰标本中为82%,咽拭子标本中为46%,脓液标本中为39%。作为伴随微生物,发现了尤其是流感嗜血杆菌、金黄色葡萄球菌(在咽拭子和脓液标本中)和肠道杆菌。在猩红热病例中,高达60%的病例存在金黄色葡萄球菌。在所有送检材料的22%以及所有痰标本的45%中,从各种伴随微生物中分离出了耐氨苄西林菌株。