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[从咽拭子和脓性物质中分离出的β-溶血性链球菌的抗生素敏感性]

[Antibiotic sensitivity of beta-hemolytic streptococci isolated from throat swabs and purulent material].

作者信息

Jachna-Sawicka Katarzyna, Pietrzak Anna, Bogiel Tomasz, Gospodarek Eugenia

机构信息

Katedra i Zakład Mikrobiologii, Collegium Medicum im. A. Jurasza w Bydgoszczy UMK w Toruniu.

出版信息

Med Dosw Mikrobiol. 2010;62(4):309-17.

Abstract

The aim of this study was to evaluate the prevalence and susceptibility of beta-hemolytic streptococci isolated from throat swabs (142--29.9%) and purulent material (333--70.1%) taken from patients treated at University Hospital dr. A. Jurasz in Bydgoszcz Collegium Medicum. L. Rydygier in Bydgoszcz, Nicolaus Copernicus University in Torun in 2005-2009. Of the 475 tested strains, 156 (32.8%) were identified as S. pyogenes. This species accounted for 38.8% of strains isolated from purulent material and 19.0% of swabs from the throat. Among the strains isolated from throat swabs of 62 (43.7%) were identified as Streptococcus group C. Only 5.1% strains were identified as Streptococcus group F. All strains of beta-hemolytic streptococci were susceptible to ampicillin or penicillin, fluoroquinolones, vancomycin and linezolid. Erythromycin-susceptible strains was 83.8%, and 89.1% for clindamycin. A total of 51.3% of erythromycin resistance strains had the cMLS(B) phenotype (63.3% for strains from throat swabs and 46.3% of the purulent materials). Sensitivity to tetracycline was characterized by 51.2% of strains of beta-hemolytic streptococci. The percentage of strains susceptible to this antibiotic among isolates from throat swabs was 63.1%, and purulent material--48.0%. The lowest percentage of strains susceptible to tetracycline (14.1%) were found among S. agalactiae and Streptococcus group G (33.6%) strains. During the study time, saw an increase in the percentage of strains susceptible to tetracycline and erythromycin.

摘要

本研究旨在评估从2005年至2009年在比得哥什的A. 尤拉什大学医院、比得哥什的L. 雷迪吉尔医学院、托伦的哥白尼大学接受治疗的患者的咽喉拭子(142份,占29.9%)和脓性物质(333份,占70.1%)中分离出的β溶血性链球菌的患病率和药敏性。在475株受试菌株中,156株(32.8%)被鉴定为化脓性链球菌。该菌种占从脓性物质中分离出的菌株的38.8%,占咽喉拭子菌株的19.0%。在从咽喉拭子中分离出的菌株中,62株(43.7%)被鉴定为C组链球菌。仅5.1%的菌株被鉴定为F组链球菌。所有β溶血性链球菌菌株对氨苄西林或青霉素、氟喹诺酮类、万古霉素和利奈唑胺敏感。对红霉素敏感的菌株为83.8%,对克林霉素敏感的菌株为89.1%。共有51.3%的红霉素耐药菌株具有cMLS(B)表型(咽喉拭子菌株为63.3%,脓性物质菌株为46.3%)。51.2%的β溶血性链球菌菌株对四环素敏感。从咽喉拭子分离出的菌株中对该抗生素敏感的百分比为63.1%,脓性物质分离出的菌株为48.0%。在无乳链球菌和G组链球菌(33.6%)菌株中发现对四环素敏感的菌株百分比最低(14.1%)。在研究期间,发现对四环素和红霉素敏感的菌株百分比有所增加。

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